Regulation and directed inhibition of ECP production by human neutrophils

Regulation and directed inhibition of ECP production by human neutrophils

BackgroundNeutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein (ECP) is a critical inflammatory mediator. Although ECP production is attributed to eosinophils, we reported that ECP is also present in neutrophils from allergic patients where, in co...

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Bibliographic Details
Main Authors: Antonio Vega-Rioja, Pedro Chacón, Lourdes Fernández-Delgado, Bouchra Doukkali, Alberto del Valle Rodríguez, James R. Perkins, Juan A. G. Ranea, Leticia Dominguez-Cereijo, Beatriz María Pérez-Machuca, Ricardo Palacios, David Rodríguez, Javier Monteseirín, David Ribas-Pérez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
allergy
asthma
IgE
ECP
allergen
cell signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015529/full

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