Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation
Introduction: Fine Needle Aspiration Cytology (FNAC) is quick, simple, inexpensive and minimally invasive technique used to diagnose different types of lesions located in neck. Palpable lesions in neck region can arise from various structures like, lymph node, thyroid, salivary gland, soft tissu...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2016-07-01
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| Series: | National Journal of Laboratory Medicine |
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| Online Access: | http://www.njlm.net/articles/PDF/2147/20415_F(GH)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdf |
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| author | Namrata Sharma Sangeeta Sharma Mahuya Sarkar Rani Bansal Anjali Khare Davendra Swarup Priya Gupta Mitali Singhal |
| author_facet | Namrata Sharma Sangeeta Sharma Mahuya Sarkar Rani Bansal Anjali Khare Davendra Swarup Priya Gupta Mitali Singhal |
| author_sort | Namrata Sharma |
| collection | DOAJ |
| description | Introduction: Fine Needle Aspiration Cytology (FNAC) is quick,
simple, inexpensive and minimally invasive technique used to
diagnose different types of lesions located in neck. Palpable
lesions in neck region can arise from various structures like,
lymph node, thyroid, salivary gland, soft tissues, and blood
vessels.
Aim: To study the spectrum of pathological lesions in neck
masses diagnosed on FNAC and to evaluate its accuracy
by correlating cytological findings with histopathological
diagnosis.
Materials and Methods: A retrospective as well as
prospective study was conducted from September 2012 to
August 2015. Cytological diagnosis was made and correlated
with histopathological diagnosis. Data analysis was done by
Statistical Package for the Social Sciences (SPSS) Version 19.
The data were expressed as frequency and percentage.
Results: Out of total 678 Fine needle procedures, (89%) were
inflammatory, (5.4%) were malignant and (2.9%) were benign.
(2.5%) were inconclusive. Out of total 400 Lymph node lesions,
reactive lymphoid hyperplasia/nonspecific lymphadenitis, was
the commonest, (50.7%). In all 198 cases of thyroid lesions
were diagnosed, in which incidence rate of colloid goitre was
74.2%.
40 cases of salivary gland lesions were found among which
chronic sialadenitis was the commonest, 17 cases (70.8%). The
sensitivity, specificity of FNAC of lymph nodes was 94.12%,
100% respectively. The diagnostic accuracy was 96%. The
sensitivity, specificity and diagnostic accuracy of FNAC of
thyroid glands and salivary glands were all 100%.
Conclusion: Neck swellings are a very common condition
encountered. FNAC is a simple and effective method of
assessing neck lumps. FNAC has high accuracy rate to
differentiate infective conditions from neoplastic ones and
avoids unnecessary surgeries. Thus FNAC can be a helpful
investigation in the diagnosis of neck swellings. |
| first_indexed | 2024-04-13T15:52:08Z |
| format | Article |
| id | doaj.art-a2600f7daaef4a7590e67ccb299115ab |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-04-13T15:52:08Z |
| publishDate | 2016-07-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-a2600f7daaef4a7590e67ccb299115ab2022-12-22T02:40:48ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822016-07-0153PO58PO6310.7860/NJLM/2016/20415.2147Study of Pathological Spectrum of Neck Lesions with Cytohistopathological CorrelationNamrata Sharma0Sangeeta Sharma1Mahuya Sarkar2Rani Bansal3Anjali Khare4Davendra Swarup5Priya Gupta6Mitali Singhal7Junior Resident, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor and Head, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Assistant Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Assistant Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Introduction: Fine Needle Aspiration Cytology (FNAC) is quick, simple, inexpensive and minimally invasive technique used to diagnose different types of lesions located in neck. Palpable lesions in neck region can arise from various structures like, lymph node, thyroid, salivary gland, soft tissues, and blood vessels. Aim: To study the spectrum of pathological lesions in neck masses diagnosed on FNAC and to evaluate its accuracy by correlating cytological findings with histopathological diagnosis. Materials and Methods: A retrospective as well as prospective study was conducted from September 2012 to August 2015. Cytological diagnosis was made and correlated with histopathological diagnosis. Data analysis was done by Statistical Package for the Social Sciences (SPSS) Version 19. The data were expressed as frequency and percentage. Results: Out of total 678 Fine needle procedures, (89%) were inflammatory, (5.4%) were malignant and (2.9%) were benign. (2.5%) were inconclusive. Out of total 400 Lymph node lesions, reactive lymphoid hyperplasia/nonspecific lymphadenitis, was the commonest, (50.7%). In all 198 cases of thyroid lesions were diagnosed, in which incidence rate of colloid goitre was 74.2%. 40 cases of salivary gland lesions were found among which chronic sialadenitis was the commonest, 17 cases (70.8%). The sensitivity, specificity of FNAC of lymph nodes was 94.12%, 100% respectively. The diagnostic accuracy was 96%. The sensitivity, specificity and diagnostic accuracy of FNAC of thyroid glands and salivary glands were all 100%. Conclusion: Neck swellings are a very common condition encountered. FNAC is a simple and effective method of assessing neck lumps. FNAC has high accuracy rate to differentiate infective conditions from neoplastic ones and avoids unnecessary surgeries. Thus FNAC can be a helpful investigation in the diagnosis of neck swellings.http://www.njlm.net/articles/PDF/2147/20415_F(GH)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdffine needle aspiration cytology (fnac)goiternonspecific lymphadenitispleomorphic adenoma. |
| spellingShingle | Namrata Sharma Sangeeta Sharma Mahuya Sarkar Rani Bansal Anjali Khare Davendra Swarup Priya Gupta Mitali Singhal Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation National Journal of Laboratory Medicine fine needle aspiration cytology (fnac) goiter nonspecific lymphadenitis pleomorphic adenoma. |
| title | Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation |
| title_full | Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation |
| title_fullStr | Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation |
| title_full_unstemmed | Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation |
| title_short | Study of Pathological Spectrum of Neck Lesions with Cytohistopathological Correlation |
| title_sort | study of pathological spectrum of neck lesions with cytohistopathological correlation |
| topic | fine needle aspiration cytology (fnac) goiter nonspecific lymphadenitis pleomorphic adenoma. |
| url | http://www.njlm.net/articles/PDF/2147/20415_F(GH)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdf |
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