Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy

Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy

Abstract Background Vaccination of mice with tumors treated with Doxorubicin promotes a T cell immunity that relies on dendritic cell (DC) activation and is responsible for tumor control in vaccinated animals. Despite Doxorubicin in combination with Cyclophosphamide (A/C) is widely used to treat bre...

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Bibliographic Details
Main Authors: David A. Bernal-Estévez, Oscar García, Ramiro Sánchez, Carlos A. Parra-López
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Cancer
Subjects:
Breast cancer
Chemotherapy
Neoadjuvant
T cells
Dendritic cells
Doxorubicin
Online Access:http://link.springer.com/article/10.1186/s12885-017-3982-1

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