Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women
Background:To evaluate the relation between raised serum uric acid level and fetal outcome. Methods:This Cohort study was conducted at Department of Obstetrics and Gynaecology, Services Hospital, Lahore, to compare the risk of poor fetal outcome in hyperuricemic and normouricemic pre-eclamptic patie...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2015-06-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/286 |
| _version_ | 1828945676156796928 |
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| author | Aneela Khaleeq |
| author_facet | Aneela Khaleeq |
| author_sort | Aneela Khaleeq |
| collection | DOAJ |
| description | Background:To evaluate the relation between raised serum uric acid level and fetal outcome.
Methods:This Cohort study was conducted at Department of Obstetrics and Gynaecology, Services Hospital, Lahore, to compare the risk of poor fetal outcome in hyperuricemic and normouricemic pre-eclamptic patients. A total of 300 patients with the diagnosis of pre-eclampsia were included in the study and serum uric acid levels were obtained in all the patients. They were divided into two groups: Group A: Pre-eclamptic Normouricemic; Group B: Pre-eclamptic Hyperuricemic. All patients were followed after delivery for fetal outcome and results were compared in both groups.
Results: The mean maternal age was 28.60 ± 3.308 years. The mean gestational age was 36.85 ± 0.59 weeks. The mean uric acid level of the patients at presentation was 5.067 ± 1.74 mg/dl. The mean uric acid level in group A was 3.64 ± 0.73 mg/dl and in group B was 7.98 ± 0.85 mg/dl. In group A, 9.3% newborns were found small-for-gestational-age (SGA), whereas in Group B, 23.3% newborns were found having SGA. The relative risk was calculated for development of SGA in hyperuricemia and was found significant (RR=2.5; 95% CI: 1.40- 4.45).
Conclusion: Serum uric acid level measurement is a useful and inexpensive marker for predicting pre-eclampsia and fetal growth retardation in women presenting with gestational hypertension. |
| first_indexed | 2024-12-14T04:57:06Z |
| format | Article |
| id | doaj.art-a2609ae85ef94843b5d8e3d727f4b4f2 |
| institution | Directory Open Access Journal |
| issn | 1683-3562 1683-3570 |
| language | English |
| last_indexed | 2024-12-14T04:57:06Z |
| publishDate | 2015-06-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj.art-a2609ae85ef94843b5d8e3d727f4b4f22022-12-21T23:16:20ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702015-06-01192Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic WomenAneela Khaleeq0Department of Gynaecology/Obstetrics, King Edward Medical College, LahoreBackground:To evaluate the relation between raised serum uric acid level and fetal outcome. Methods:This Cohort study was conducted at Department of Obstetrics and Gynaecology, Services Hospital, Lahore, to compare the risk of poor fetal outcome in hyperuricemic and normouricemic pre-eclamptic patients. A total of 300 patients with the diagnosis of pre-eclampsia were included in the study and serum uric acid levels were obtained in all the patients. They were divided into two groups: Group A: Pre-eclamptic Normouricemic; Group B: Pre-eclamptic Hyperuricemic. All patients were followed after delivery for fetal outcome and results were compared in both groups. Results: The mean maternal age was 28.60 ± 3.308 years. The mean gestational age was 36.85 ± 0.59 weeks. The mean uric acid level of the patients at presentation was 5.067 ± 1.74 mg/dl. The mean uric acid level in group A was 3.64 ± 0.73 mg/dl and in group B was 7.98 ± 0.85 mg/dl. In group A, 9.3% newborns were found small-for-gestational-age (SGA), whereas in Group B, 23.3% newborns were found having SGA. The relative risk was calculated for development of SGA in hyperuricemia and was found significant (RR=2.5; 95% CI: 1.40- 4.45). Conclusion: Serum uric acid level measurement is a useful and inexpensive marker for predicting pre-eclampsia and fetal growth retardation in women presenting with gestational hypertension.https://www.journalrmc.com/index.php/JRMC/article/view/286HyperuricemiaPre-eclampsiaFetal outcome |
| spellingShingle | Aneela Khaleeq Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women Journal of Rawalpindi Medical College Hyperuricemia Pre-eclampsia Fetal outcome |
| title | Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women |
| title_full | Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women |
| title_fullStr | Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women |
| title_full_unstemmed | Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women |
| title_short | Hyperuricemia as a Predictor of Poor Fetal Outcome in Pre-Eclamptic Women |
| title_sort | hyperuricemia as a predictor of poor fetal outcome in pre eclamptic women |
| topic | Hyperuricemia Pre-eclampsia Fetal outcome |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/286 |
| work_keys_str_mv | AT aneelakhaleeq hyperuricemiaasapredictorofpoorfetaloutcomeinpreeclampticwomen |