Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality

Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality

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Summary: Tumor-associated macrophages (TAMs) play an important role in tumor immunity and comprise of subsets that have distinct phenotype, function, and ontology. Transcriptomic analyses of human medulloblastoma, the most common malignant pediatric brain cancer, showed that medulloblastomas (MBs) w...

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Bibliographic Details
Main Authors: Mai T. Dang, Michael V. Gonzalez, Krutika S. Gaonkar, Komal S. Rathi, Patricia Young, Sherjeel Arif, Li Zhai, Zahidul Alam, Samir Devalaraja, Tsun Ki Jerrick To, Ian W. Folkert, Pichai Raman, Jo Lynne Rokita, Daniel Martinez, Jaclyn N. Taroni, Joshua A. Shapiro, Casey S. Greene, Candace Savonen, Fernanda Mafra, Hakon Hakonarson, Tom Curran, Malay Haldar
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472100231X

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http://www.sciencedirect.com/science/article/pii/S221112472100231X

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