Relative telomere length and oxidative DNA damage in hypertrophic ligamentum flavum of lumbar spinal stenosis

Relative telomere length and oxidative DNA damage in hypertrophic ligamentum flavum of lumbar spinal stenosis

Background Lumbar spinal stenosis (LSS) is a common cause of low back pain with degenerative spinal change in older adults. Telomeres are repetitive nucleoprotein DNA sequences of TTAGGG at the ends of chromosomes. Oxidative stress originates from an imbalance in pro-oxidant and antioxidant homeosta...

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Bibliographic Details
Main Authors: Sinsuda Dechsupa, Wicharn Yingsakmongkol, Worawat Limthongkul, Weerasak Singhatanadgige, Sittisak Honsawek
Format: Article
Language:English
Published: PeerJ Inc. 2018-08-01
Series:PeerJ
Subjects:
Relative telomere length
8-OHdG
SA-beta-gal staining
Ligamentum flavum
Lumbar spinal stenosis
Online Access:https://peerj.com/articles/5381.pdf

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