Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from <i>Sphaerococcus coronopifolius</i>

Cytotoxic Mechanism of Sphaerodactylomelol, an Uncommon Bromoditerpene Isolated from <i>Sphaerococcus coronopifolius</i>

Marine natural products have exhibited uncommon chemical structures with relevant antitumor properties highlighting their potential to inspire the development of new anticancer agents. The goal of this work was to study the antitumor activities of the brominated diterpene sphaerodactylomelol, a rare...

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Bibliographic Details
Main Authors: Celso Alves, Joana Silva, Susete Pinteus, Eva Alonso, Rebeca Alvariño, Adriana Duarte, Diorge Marmitt, Márcia Inês Goettert, Helena Gaspar, Amparo Alfonso, Maria C. Alpoim, Luis M. Botana, Rui Pedrosa
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
breast cancer
red algae
oxidative stress
marine natural products
apoptosis
DNA damage
Online Access:https://www.mdpi.com/1420-3049/26/5/1374

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