“I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa
Abstract Background People living with HIV need to take lifelong, combination antiretroviral therapy (cART), but there have been only limited explorations of how factors affecting adherence can change over the course of an individual’s lifetime. Methods We carried out a qualitative study of men and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07667-x |
| _version_ | 1811215728751149056 |
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| author | Marian Loveday Jennifer Furin Sindisiwe Hlangu Tasneem Naidoo |
| author_facet | Marian Loveday Jennifer Furin Sindisiwe Hlangu Tasneem Naidoo |
| author_sort | Marian Loveday |
| collection | DOAJ |
| description | Abstract Background People living with HIV need to take lifelong, combination antiretroviral therapy (cART), but there have been only limited explorations of how factors affecting adherence can change over the course of an individual’s lifetime. Methods We carried out a qualitative study of men and women living with HIV in KwaZulu, Natal, South Africa who were prescribed cART and who had periods of higher and lower adherence. Results 18 individuals participated in open-ended interviews. Using a dynamic theory of adherence, we identified factual, relational, and experiential factors that were associated with adherence and non-adherence to cART. Periods of non-adherence were commonly reported. Participants described relationships and experiences as being important influences on their ability to adhere to cART throughout their treatment journeys. Conclusions Periods of non-adherence to cART are common. While many cART counseling models are based on conveying facts to people prescribed cART, providing opportunities for supportive relationship where people can process their varied experiences is likely important to maintaining health for people living with HIV. |
| first_indexed | 2024-04-12T06:27:11Z |
| format | Article |
| id | doaj.art-a26b4d641258461b8c3430c2fca92b18 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-12T06:27:11Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-a26b4d641258461b8c3430c2fca92b182022-12-22T03:44:07ZengBMCBMC Infectious Diseases1471-23342022-08-0122111110.1186/s12879-022-07667-x“I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South AfricaMarian Loveday0Jennifer Furin1Sindisiwe Hlangu2Tasneem Naidoo3HIV Prevention Research Unit, South African Medical Research CouncilDepartment of Global Health and Social Medicine, Harvard Medical SchoolHIV Prevention Research Unit, South African Medical Research CouncilR. K. Khan Hospital HAST Unit, Department of HealthAbstract Background People living with HIV need to take lifelong, combination antiretroviral therapy (cART), but there have been only limited explorations of how factors affecting adherence can change over the course of an individual’s lifetime. Methods We carried out a qualitative study of men and women living with HIV in KwaZulu, Natal, South Africa who were prescribed cART and who had periods of higher and lower adherence. Results 18 individuals participated in open-ended interviews. Using a dynamic theory of adherence, we identified factual, relational, and experiential factors that were associated with adherence and non-adherence to cART. Periods of non-adherence were commonly reported. Participants described relationships and experiences as being important influences on their ability to adhere to cART throughout their treatment journeys. Conclusions Periods of non-adherence to cART are common. While many cART counseling models are based on conveying facts to people prescribed cART, providing opportunities for supportive relationship where people can process their varied experiences is likely important to maintaining health for people living with HIV.https://doi.org/10.1186/s12879-022-07667-xSouth AfricaHIVAntiretroviral therapyAdherence |
| spellingShingle | Marian Loveday Jennifer Furin Sindisiwe Hlangu Tasneem Naidoo “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa BMC Infectious Diseases South Africa HIV Antiretroviral therapy Adherence |
| title | “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa |
| title_full | “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa |
| title_fullStr | “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa |
| title_full_unstemmed | “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa |
| title_short | “I am alive because of her”: factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa |
| title_sort | i am alive because of her factors affecting adherence to combination antiretroviral therapy among people living with hiv in kwazulu natal south africa |
| topic | South Africa HIV Antiretroviral therapy Adherence |
| url | https://doi.org/10.1186/s12879-022-07667-x |
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