Why has the epidemiology of RSV changed during the COVID-19 pandemic?
Summary: The coronavirus disease 2019 (COVID-19) pandemic has drastically perturbed the epidemiology of Respiratory Syncytial Virus (RSV) respiratory tract infections in children. The reasons for this are not clear. In this article, we review the current literature and critically discuss the differe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | EClinicalMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589537023002663 |
| _version_ | 1827906362170933248 |
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| author | Bahaa Abu-Raya Marina Viñeta Paramo Frederic Reicherz Pascal Michel Lavoie |
| author_facet | Bahaa Abu-Raya Marina Viñeta Paramo Frederic Reicherz Pascal Michel Lavoie |
| author_sort | Bahaa Abu-Raya |
| collection | DOAJ |
| description | Summary: The coronavirus disease 2019 (COVID-19) pandemic has drastically perturbed the epidemiology of Respiratory Syncytial Virus (RSV) respiratory tract infections in children. The reasons for this are not clear. In this article, we review the current literature and critically discuss the different theories to explain why the epidemiology of RSV has changed during the COVID-19 pandemic. Proposed mechanisms include decreased viral immunity in vulnerable age groups caused by the prolonged lack of RSV circulation early in the pandemic, potential Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2)-induced immune dysregulation, viral interactions between SARS-CoV-2 and RSV, and modifications in health-seeking behaviors as well as heath systems factors. Research in viral genomics and phylogeny, and more robust immunology research is needed to guide RSV prevention and health care resource planning. |
| first_indexed | 2024-03-13T00:55:22Z |
| format | Article |
| id | doaj.art-a26b561ab6f340669fbcdf793262b698 |
| institution | Directory Open Access Journal |
| issn | 2589-5370 |
| language | English |
| last_indexed | 2024-03-13T00:55:22Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | EClinicalMedicine |
| spelling | doaj.art-a26b561ab6f340669fbcdf793262b6982023-07-07T04:27:47ZengElsevierEClinicalMedicine2589-53702023-07-0161102089Why has the epidemiology of RSV changed during the COVID-19 pandemic?Bahaa Abu-Raya0Marina Viñeta Paramo1Frederic Reicherz2Pascal Michel Lavoie3Department of Pediatrics, University of British Columbia, Vancouver, Canada; British Columbia Children's Hospital Research Institute, Vancouver, Canada; Corresponding author. Department of Pediatrics, University of British Columbia, Vancouver, Canada.Department of Pediatrics, University of British Columbia, Vancouver, Canada; British Columbia Children's Hospital Research Institute, Vancouver, CanadaDepartment of Pediatrics, University of British Columbia, Vancouver, Canada; British Columbia Children's Hospital Research Institute, Vancouver, CanadaDepartment of Pediatrics, University of British Columbia, Vancouver, Canada; British Columbia Children's Hospital Research Institute, Vancouver, CanadaSummary: The coronavirus disease 2019 (COVID-19) pandemic has drastically perturbed the epidemiology of Respiratory Syncytial Virus (RSV) respiratory tract infections in children. The reasons for this are not clear. In this article, we review the current literature and critically discuss the different theories to explain why the epidemiology of RSV has changed during the COVID-19 pandemic. Proposed mechanisms include decreased viral immunity in vulnerable age groups caused by the prolonged lack of RSV circulation early in the pandemic, potential Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2)-induced immune dysregulation, viral interactions between SARS-CoV-2 and RSV, and modifications in health-seeking behaviors as well as heath systems factors. Research in viral genomics and phylogeny, and more robust immunology research is needed to guide RSV prevention and health care resource planning.http://www.sciencedirect.com/science/article/pii/S2589537023002663RSVResurgenceWaning immunityCOVID-19Co-infection |
| spellingShingle | Bahaa Abu-Raya Marina Viñeta Paramo Frederic Reicherz Pascal Michel Lavoie Why has the epidemiology of RSV changed during the COVID-19 pandemic? EClinicalMedicine RSV Resurgence Waning immunity COVID-19 Co-infection |
| title | Why has the epidemiology of RSV changed during the COVID-19 pandemic? |
| title_full | Why has the epidemiology of RSV changed during the COVID-19 pandemic? |
| title_fullStr | Why has the epidemiology of RSV changed during the COVID-19 pandemic? |
| title_full_unstemmed | Why has the epidemiology of RSV changed during the COVID-19 pandemic? |
| title_short | Why has the epidemiology of RSV changed during the COVID-19 pandemic? |
| title_sort | why has the epidemiology of rsv changed during the covid 19 pandemic |
| topic | RSV Resurgence Waning immunity COVID-19 Co-infection |
| url | http://www.sciencedirect.com/science/article/pii/S2589537023002663 |
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