Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions
Alkaloids are a large and structurally diverse group of marine-derived natural products. Most marine-derived alkaloids are biologically active and show promising applications in modern (agro)chemical, pharmaceutical, and fine chemical industries. Different approaches have been established to access...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/20/6/368 |
| _version_ | 1797485028635049984 |
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| author | Bi-Shuang Chen Di Zhang Fayene Zeferino Ribeiro de Souza Lan Liu |
| author_facet | Bi-Shuang Chen Di Zhang Fayene Zeferino Ribeiro de Souza Lan Liu |
| author_sort | Bi-Shuang Chen |
| collection | DOAJ |
| description | Alkaloids are a large and structurally diverse group of marine-derived natural products. Most marine-derived alkaloids are biologically active and show promising applications in modern (agro)chemical, pharmaceutical, and fine chemical industries. Different approaches have been established to access these marine-derived alkaloids. Among these employed methods, biotechnological approaches, namely, (chemo)enzymatic synthesis, have significant potential for playing a central role in alkaloid production on an industrial scale. In this review, we discuss research progress on marine-derived alkaloid synthesis via enzymatic reactions and note the advantages and disadvantages of their applications for industrial production, as well as green chemistry for marine natural product research. |
| first_indexed | 2024-03-09T23:12:56Z |
| format | Article |
| id | doaj.art-a270ec50a8e3439190a7461ade162c5f |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-09T23:12:56Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-a270ec50a8e3439190a7461ade162c5f2023-11-23T17:41:01ZengMDPI AGMarine Drugs1660-33972022-05-0120636810.3390/md20060368Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic ReactionsBi-Shuang Chen0Di Zhang1Fayene Zeferino Ribeiro de Souza2Lan Liu3School of Marine Sciences, Sun Yat-Sen University, Zhuhai 519082, ChinaSchool of Marine Sciences, Sun Yat-Sen University, Zhuhai 519082, ChinaCentro Universitário Planalto do Distrito Federal, Universidade Virtual do Estado de São Paulo (UNIPLAN), Campus Bauru 17014-350, BrazilSchool of Marine Sciences, Sun Yat-Sen University, Zhuhai 519082, ChinaAlkaloids are a large and structurally diverse group of marine-derived natural products. Most marine-derived alkaloids are biologically active and show promising applications in modern (agro)chemical, pharmaceutical, and fine chemical industries. Different approaches have been established to access these marine-derived alkaloids. Among these employed methods, biotechnological approaches, namely, (chemo)enzymatic synthesis, have significant potential for playing a central role in alkaloid production on an industrial scale. In this review, we discuss research progress on marine-derived alkaloid synthesis via enzymatic reactions and note the advantages and disadvantages of their applications for industrial production, as well as green chemistry for marine natural product research.https://www.mdpi.com/1660-3397/20/6/368alkaloidsnatural productsynthesisbiotechnological approachesenzymatic reactionschemoenzymatic strategies |
| spellingShingle | Bi-Shuang Chen Di Zhang Fayene Zeferino Ribeiro de Souza Lan Liu Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions Marine Drugs alkaloids natural product synthesis biotechnological approaches enzymatic reactions chemoenzymatic strategies |
| title | Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions |
| title_full | Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions |
| title_fullStr | Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions |
| title_full_unstemmed | Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions |
| title_short | Recent Advances in the Synthesis of Marine-Derived Alkaloids via Enzymatic Reactions |
| title_sort | recent advances in the synthesis of marine derived alkaloids via enzymatic reactions |
| topic | alkaloids natural product synthesis biotechnological approaches enzymatic reactions chemoenzymatic strategies |
| url | https://www.mdpi.com/1660-3397/20/6/368 |
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