Nanonutraceuticals: The New Frontier of Supplementary Food
In the last few decades, the combination between nanotechnology and nutraceutics has gained the attention of several research groups. Nutraceuticals are considered as active compounds, abundant in natural products, showing beneficial effects on human health. Unfortunately, the uses, and consequently...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/11/3/792 |
| _version_ | 1797540721373216768 |
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| author | Donatella Paolino Antonia Mancuso Maria Chiara Cristiano Francesca Froiio Narimane Lammari Christian Celia Massimo Fresta |
| author_facet | Donatella Paolino Antonia Mancuso Maria Chiara Cristiano Francesca Froiio Narimane Lammari Christian Celia Massimo Fresta |
| author_sort | Donatella Paolino |
| collection | DOAJ |
| description | In the last few decades, the combination between nanotechnology and nutraceutics has gained the attention of several research groups. Nutraceuticals are considered as active compounds, abundant in natural products, showing beneficial effects on human health. Unfortunately, the uses, and consequently the health benefits, of many nutraceutical products are limited by their unsuitable chemico-physical features. For example, many nutraceuticals are characterized by low water solubility, low stability and high susceptibility to light and oxygen, poor absorption and potential chemical modifications after their administration. Based on the potential efficacy of nutraceuticals and on their limiting features, nanotechnology could be considered a revolutionary innovation in empowering the beneficial properties of nutraceuticals on human health, thus enhancing their efficacy in several diseases. For this reason, nanotechnology could represent a new frontier in supplementary food. In this review, the most recent nanotechnological approaches are discussed, focusing on their ability to improve the bioavailability of the most common nutraceuticals, providing an overview regarding both the advantages and the possible limitations of the use of several nanodelivery systems. In fact, although the efficacy of smart nanocarriers in improving health benefits deriving from nutraceuticals has been widely demonstrated, the conflicting opinions on the mechanism of action of some nanosystems still reduce their applicability in the therapeutic field. |
| first_indexed | 2024-03-10T13:05:04Z |
| format | Article |
| id | doaj.art-a272622f3f914d4f8133d2acc6c57dd1 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T13:05:04Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-a272622f3f914d4f8133d2acc6c57dd12023-11-21T11:13:28ZengMDPI AGNanomaterials2079-49912021-03-0111379210.3390/nano11030792Nanonutraceuticals: The New Frontier of Supplementary FoodDonatella Paolino0Antonia Mancuso1Maria Chiara Cristiano2Francesca Froiio3Narimane Lammari4Christian Celia5Massimo Fresta6Department of Experimental and Clinical Medicine, University of Catanzaro “Magna Graecia”, Viale Europa s.n.c., I-88100 Catanzaro, ItalyDepartment of Health Sciences, University of Catanzaro “Magna Graecia”, Viale Europa s.n.c., I-88100 Catanzaro, ItalyDepartment of Experimental and Clinical Medicine, University of Catanzaro “Magna Graecia”, Viale Europa s.n.c., I-88100 Catanzaro, ItalyDepartment of Experimental and Clinical Medicine, University of Catanzaro “Magna Graecia”, Viale Europa s.n.c., I-88100 Catanzaro, ItalyEnvironmental Process Engineering Laboratory, University Constantine 3, Salah Boubnider, 25000 Constantine, AlgeriaDepartment of Pharmacy, University of Chieti-Pescara “G. d’Annunzio”, Via dei Vestini 31, I-66100 Chieti, ItalyDepartment of Health Sciences, University of Catanzaro “Magna Graecia”, Viale Europa s.n.c., I-88100 Catanzaro, ItalyIn the last few decades, the combination between nanotechnology and nutraceutics has gained the attention of several research groups. Nutraceuticals are considered as active compounds, abundant in natural products, showing beneficial effects on human health. Unfortunately, the uses, and consequently the health benefits, of many nutraceutical products are limited by their unsuitable chemico-physical features. For example, many nutraceuticals are characterized by low water solubility, low stability and high susceptibility to light and oxygen, poor absorption and potential chemical modifications after their administration. Based on the potential efficacy of nutraceuticals and on their limiting features, nanotechnology could be considered a revolutionary innovation in empowering the beneficial properties of nutraceuticals on human health, thus enhancing their efficacy in several diseases. For this reason, nanotechnology could represent a new frontier in supplementary food. In this review, the most recent nanotechnological approaches are discussed, focusing on their ability to improve the bioavailability of the most common nutraceuticals, providing an overview regarding both the advantages and the possible limitations of the use of several nanodelivery systems. In fact, although the efficacy of smart nanocarriers in improving health benefits deriving from nutraceuticals has been widely demonstrated, the conflicting opinions on the mechanism of action of some nanosystems still reduce their applicability in the therapeutic field.https://www.mdpi.com/2079-4991/11/3/792nutraceuticalsnanocarrierssmart deliveryhealth benefitssupplementary food |
| spellingShingle | Donatella Paolino Antonia Mancuso Maria Chiara Cristiano Francesca Froiio Narimane Lammari Christian Celia Massimo Fresta Nanonutraceuticals: The New Frontier of Supplementary Food Nanomaterials nutraceuticals nanocarriers smart delivery health benefits supplementary food |
| title | Nanonutraceuticals: The New Frontier of Supplementary Food |
| title_full | Nanonutraceuticals: The New Frontier of Supplementary Food |
| title_fullStr | Nanonutraceuticals: The New Frontier of Supplementary Food |
| title_full_unstemmed | Nanonutraceuticals: The New Frontier of Supplementary Food |
| title_short | Nanonutraceuticals: The New Frontier of Supplementary Food |
| title_sort | nanonutraceuticals the new frontier of supplementary food |
| topic | nutraceuticals nanocarriers smart delivery health benefits supplementary food |
| url | https://www.mdpi.com/2079-4991/11/3/792 |
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