Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2021-01-01
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| Series: | Environmental Chemistry and Ecotoxicology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590182621000035 |
| _version_ | 1819002915451305984 |
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| author | N. Muniyappan M. Pandeeswaran Augustine Amalraj |
| author_facet | N. Muniyappan M. Pandeeswaran Augustine Amalraj |
| author_sort | N. Muniyappan |
| collection | DOAJ |
| description | Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles. |
| first_indexed | 2024-12-20T23:12:41Z |
| format | Article |
| id | doaj.art-a278f990158342e99091a9ef1ecb8fee |
| institution | Directory Open Access Journal |
| issn | 2590-1826 |
| language | English |
| last_indexed | 2024-12-20T23:12:41Z |
| publishDate | 2021-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Environmental Chemistry and Ecotoxicology |
| spelling | doaj.art-a278f990158342e99091a9ef1ecb8fee2022-12-21T19:23:42ZengKeAi Communications Co., Ltd.Environmental Chemistry and Ecotoxicology2590-18262021-01-013117124Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activitiesN. Muniyappan0M. Pandeeswaran1Augustine Amalraj2Department of Chemistry, Saraswathi Narayanan College, Madurai 625 022, Tamil Nadu, India; Corresponding authors.Department of Chemistry, GTN Arts College, Dindigul 624 005, Tamil Nadu, IndiaR&D Centre, Aurea Biolabs (P) Ltd, Kolenchery, Cochin 682 311, Kerala, India; Corresponding authors.Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles.http://www.sciencedirect.com/science/article/pii/S2590182621000035Curcuma pseudomontana rhizomeHill turmericCurcuminGold nanoparticlesBiological activities |
| spellingShingle | N. Muniyappan M. Pandeeswaran Augustine Amalraj Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities Environmental Chemistry and Ecotoxicology Curcuma pseudomontana rhizome Hill turmeric Curcumin Gold nanoparticles Biological activities |
| title | Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities |
| title_full | Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities |
| title_fullStr | Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities |
| title_full_unstemmed | Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities |
| title_short | Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities |
| title_sort | green synthesis of gold nanoparticles using curcuma pseudomontana isolated curcumin its characterization antimicrobial antioxidant and anti inflammatory activities |
| topic | Curcuma pseudomontana rhizome Hill turmeric Curcumin Gold nanoparticles Biological activities |
| url | http://www.sciencedirect.com/science/article/pii/S2590182621000035 |
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