ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
Live-attenuated strains of simian immunodeficiency virus (SIV) routinely confer apparent sterilizing immunity against pathogenic SIV challenge in rhesus macaques. Understanding the mechanisms of protection by live-attenuated SIV may provide important insights into the immune responses needed for pro...
Autors principals: | Michael D Alpert, Jackson D Harvey, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans |
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Format: | Article |
Idioma: | English |
Publicat: |
Public Library of Science (PLoS)
2012-01-01
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Col·lecció: | PLoS Pathogens |
Accés en línia: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002890&type=printable |
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