ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.

Live-attenuated strains of simian immunodeficiency virus (SIV) routinely confer apparent sterilizing immunity against pathogenic SIV challenge in rhesus macaques. Understanding the mechanisms of protection by live-attenuated SIV may provide important insights into the immune responses needed for pro...

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Main Authors: Michael D Alpert, Jackson D Harvey, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS Pathogens
在線閱讀:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002890&type=printable