Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking

Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking

Background: Although advance has been made in understanding the pathogenesis of mature T-cell neoplasms, the initiation and progression of angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), remain poorly understood. A subset of AITL/PTCL-NOS...

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Bibliographic Details
Main Authors: Shuhua Cheng, Wei Zhang, Giorgio Inghirami, Wayne Tam
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
angioimmunoblastic t cell lymphoma
clonal hematopoiesis
concurrent hematologic neoplasm
mutated hematopoietic precursor
smoking
biomarker
Online Access:https://elifesciences.org/articles/66395

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