Research progress on regenerative endodontic procedures
Regenerative endodontic procedures, based on dental pulp biology, use the basic principles of tissue engineering to promote the functional regeneration of dental pulp-dentin complexes. Good results have been achieved in the treatment of young permanent teeth with pulp necrosis or apical periodontiti...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2023-01-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.01.014 |
| _version_ | 1817978344070709248 |
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| author | DAI Xingzhu CHEN Lijuan LIANG Yuee ZHAO Wanghong |
| author_facet | DAI Xingzhu CHEN Lijuan LIANG Yuee ZHAO Wanghong |
| author_sort | DAI Xingzhu |
| collection | DOAJ |
| description | Regenerative endodontic procedures, based on dental pulp biology, use the basic principles of tissue engineering to promote the functional regeneration of dental pulp-dentin complexes. Good results have been achieved in the treatment of young permanent teeth with pulp necrosis or apical periodontitis. There have also been preliminary clinical explorations of the treatment of mature permanent teeth in recent years. The key to successful treatment is controlling infection as well as promoting tissue repair and regeneration. Moderate root canal mechanical preparation is allowed in the therapy of mature permanent teeth, while it is not recommended in the treatment of young permanent teeth. The choice of root canal irrigation and intracanal antisepsis requires a comprehensive consideration of the antibacterial effects, biological safety, and possible complications, such as crown discoloration and root canal calcification. The development of bioceramic materials provides more options for crown sealing materials, but further clinical evaluation is needed. In addition to traditional blood clot scaffolds, new types of tissue scaffolds represented by platelet-rich plasma, platelet-rich fibrin, concentrated growth factors and other platelet concentrates have been developed. Long-term and large-scale studies are needed to evaluate the actual clinical efficacy of these new scaffolds and the efficacy of their combined application with blood clots. |
| first_indexed | 2024-04-13T22:28:46Z |
| format | Article |
| id | doaj.art-a282bfffb91d42c9af955a3ef3f1beba |
| institution | Directory Open Access Journal |
| issn | 2096-1456 |
| language | zho |
| last_indexed | 2024-04-13T22:28:46Z |
| publishDate | 2023-01-01 |
| publisher | Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
| record_format | Article |
| series | 口腔疾病防治 |
| spelling | doaj.art-a282bfffb91d42c9af955a3ef3f1beba2022-12-22T02:27:00ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562023-01-01311737610.12016/j.issn.2096-1456.2023.01.014Research progress on regenerative endodontic proceduresDAI Xingzhu0CHEN Lijuan1LIANG Yuee2 ZHAO Wanghong3Department of Stomatology, Nanfang Hospital, Southern Medical University, School of Stomatology, Southern Medical UniversityDepartment of Stomatology, Nanfang Hospital, Southern Medical University, School of Stomatology, Southern Medical UniversityDepartment of Stomatology, Nanfang Hospital, Southern Medical University, School of Stomatology, Southern Medical UniversityDepartment of Stomatology, Nanfang Hospital, Southern Medical University, School of Stomatology, Southern Medical UniversityRegenerative endodontic procedures, based on dental pulp biology, use the basic principles of tissue engineering to promote the functional regeneration of dental pulp-dentin complexes. Good results have been achieved in the treatment of young permanent teeth with pulp necrosis or apical periodontitis. There have also been preliminary clinical explorations of the treatment of mature permanent teeth in recent years. The key to successful treatment is controlling infection as well as promoting tissue repair and regeneration. Moderate root canal mechanical preparation is allowed in the therapy of mature permanent teeth, while it is not recommended in the treatment of young permanent teeth. The choice of root canal irrigation and intracanal antisepsis requires a comprehensive consideration of the antibacterial effects, biological safety, and possible complications, such as crown discoloration and root canal calcification. The development of bioceramic materials provides more options for crown sealing materials, but further clinical evaluation is needed. In addition to traditional blood clot scaffolds, new types of tissue scaffolds represented by platelet-rich plasma, platelet-rich fibrin, concentrated growth factors and other platelet concentrates have been developed. Long-term and large-scale studies are needed to evaluate the actual clinical efficacy of these new scaffolds and the efficacy of their combined application with blood clots.http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.01.014regenerative endodontic procedurestissue engineeringindicationsinfection controlroot canal preparationbioceramicstissue scaffoldsplatelet concentrates |
| spellingShingle | DAI Xingzhu CHEN Lijuan LIANG Yuee ZHAO Wanghong Research progress on regenerative endodontic procedures 口腔疾病防治 regenerative endodontic procedures tissue engineering indications infection control root canal preparation bioceramics tissue scaffolds platelet concentrates |
| title | Research progress on regenerative endodontic procedures |
| title_full | Research progress on regenerative endodontic procedures |
| title_fullStr | Research progress on regenerative endodontic procedures |
| title_full_unstemmed | Research progress on regenerative endodontic procedures |
| title_short | Research progress on regenerative endodontic procedures |
| title_sort | research progress on regenerative endodontic procedures |
| topic | regenerative endodontic procedures tissue engineering indications infection control root canal preparation bioceramics tissue scaffolds platelet concentrates |
| url | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.01.014 |
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