Impact of reduced exposure to calcineurin inhibitors on the development of de novo DSA: a cohort of non-immunized first kidney graft recipients between 2007 and 2014

Impact of reduced exposure to calcineurin inhibitors on the development of de novo DSA: a cohort of non-immunized first kidney graft recipients between 2007 and 2014

Abstract Background In low-immunological risk kidney transplant recipients (KTRs), reduced exposure to calcineurin inhibitor (CNI) appears particularly attractive for avoiding adverse events, but may increase the risk of developing de novo Donor Specific Antibodies (dnDSA). Methods CNI exposure was...

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Bibliographic Details
Main Authors: S. Girerd, J. Schikowski, N. Girerd, K. Duarte, H. Busby, N. Gambier, M. Ladrière, M. Kessler, L. Frimat, A. Aarnink
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Nephrology
Subjects:
Kidney transplantation
Calcineurin inhibitors
Donor specific antibodies
Under immunosuppression
Online Access:http://link.springer.com/article/10.1186/s12882-018-1014-2

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