Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas
The fatty acid composition of human breast milk is relevant for the energy, immunity and eicosanoid production in infants. Additionally, the antioxidant properties of foods are essential for human health. Therefore, in the present study we aimed to investigate the relationship between maternal diet...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/12/2910 |
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| author | Michela Codini Carmela Tringaniello Lina Cossignani Antonio Boccuto Alessandra Mirarchi Laura Cerquiglini Stefania Troiani Giuseppa Verducci Federica Filomena Patria Carmela Conte Samuela Cataldi Maria Rachele Ceccarini Rita Paroni Michele Dei Cas Tommaso Beccari Francesco Curcio Elisabetta Albi |
| author_facet | Michela Codini Carmela Tringaniello Lina Cossignani Antonio Boccuto Alessandra Mirarchi Laura Cerquiglini Stefania Troiani Giuseppa Verducci Federica Filomena Patria Carmela Conte Samuela Cataldi Maria Rachele Ceccarini Rita Paroni Michele Dei Cas Tommaso Beccari Francesco Curcio Elisabetta Albi |
| author_sort | Michela Codini |
| collection | DOAJ |
| description | The fatty acid composition of human breast milk is relevant for the energy, immunity and eicosanoid production in infants. Additionally, the antioxidant properties of foods are essential for human health. Therefore, in the present study we aimed to investigate the relationship between maternal diet and fatty acids composition as well as the antioxidant potential of breast milk from donors to human milk bank of Perugia’s hospital, Italy. Results were compared with infant formulas. We observed increased levels of total fatty acids and, in particular, saturated and monounsaturated fatty acids in milk from mothers fed on a vegetable and fruit-rich diet compared with a Mediterranean diet. In the same milk, a reduced antioxidant potential was found. All infant formulas resulted in richer total fatty acid content than human breast milk. Only some formulas were qualitatively similar to breast milk. Of note, the antioxidant potential of the formulas was higher or lower than the human milk with the exception of one sample. The antioxidant potential of four formulas was very high. Dietary supplementation with antioxidants has been shown to have a teratogenic effect and to increase the formation of metastases in adult. There are no data on the effects of excess antioxidants in the infants, but the possibility that they can be harmful cannot be excluded. |
| first_indexed | 2024-03-10T18:54:30Z |
| format | Article |
| id | doaj.art-a2868702609940fda6fd5b6d188718d0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T18:54:30Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-a2868702609940fda6fd5b6d188718d02023-11-20T04:51:44ZengMDPI AGMolecules1420-30492020-06-012512291010.3390/molecules25122910Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant FormulasMichela Codini0Carmela Tringaniello1Lina Cossignani2Antonio Boccuto3Alessandra Mirarchi4Laura Cerquiglini5Stefania Troiani6Giuseppa Verducci7Federica Filomena Patria8Carmela Conte9Samuela Cataldi10Maria Rachele Ceccarini11Rita Paroni12Michele Dei Cas13Tommaso Beccari14Francesco Curcio15Elisabetta Albi16Department of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Mathematics and Computer Science, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyStruttura Complessa di Neonatologia e Terapia Intensiva Neonatale– Azienda Ospedaliera Santa Maria della Misericordia—Perugia, 06129 Perugia, ItalyStruttura Complessa di Neonatologia e Terapia Intensiva Neonatale– Azienda Ospedaliera Santa Maria della Misericordia—Perugia, 06129 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, ItalyDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyDepartment of Medicine (DAME), University of Udine, 33100 Udine, ItalyDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, ItalyThe fatty acid composition of human breast milk is relevant for the energy, immunity and eicosanoid production in infants. Additionally, the antioxidant properties of foods are essential for human health. Therefore, in the present study we aimed to investigate the relationship between maternal diet and fatty acids composition as well as the antioxidant potential of breast milk from donors to human milk bank of Perugia’s hospital, Italy. Results were compared with infant formulas. We observed increased levels of total fatty acids and, in particular, saturated and monounsaturated fatty acids in milk from mothers fed on a vegetable and fruit-rich diet compared with a Mediterranean diet. In the same milk, a reduced antioxidant potential was found. All infant formulas resulted in richer total fatty acid content than human breast milk. Only some formulas were qualitatively similar to breast milk. Of note, the antioxidant potential of the formulas was higher or lower than the human milk with the exception of one sample. The antioxidant potential of four formulas was very high. Dietary supplementation with antioxidants has been shown to have a teratogenic effect and to increase the formation of metastases in adult. There are no data on the effects of excess antioxidants in the infants, but the possibility that they can be harmful cannot be excluded.https://www.mdpi.com/1420-3049/25/12/2910human milkfatty acidsPUFAantioxidant potentialinfant formulas |
| spellingShingle | Michela Codini Carmela Tringaniello Lina Cossignani Antonio Boccuto Alessandra Mirarchi Laura Cerquiglini Stefania Troiani Giuseppa Verducci Federica Filomena Patria Carmela Conte Samuela Cataldi Maria Rachele Ceccarini Rita Paroni Michele Dei Cas Tommaso Beccari Francesco Curcio Elisabetta Albi Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas Molecules human milk fatty acids PUFA antioxidant potential infant formulas |
| title | Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas |
| title_full | Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas |
| title_fullStr | Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas |
| title_full_unstemmed | Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas |
| title_short | Relationship between Fatty Acids Composition/Antioxidant Potential of Breast Milk and Maternal Diet: Comparison with Infant Formulas |
| title_sort | relationship between fatty acids composition antioxidant potential of breast milk and maternal diet comparison with infant formulas |
| topic | human milk fatty acids PUFA antioxidant potential infant formulas |
| url | https://www.mdpi.com/1420-3049/25/12/2910 |
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