A static glucose-stimulated insulin secretion (sGSIS) assay that is significantly predictive of time to diabetes reversal in the human islet bioassay

Introduction Static incubation (static glucose-stimulated insulin secretion, sGSIS) is a measure of islet secretory function. The Stimulation Index (SI; insulin produced in high glucose/insulin produced in low glucose) is currently used as a product release criterion of islet transplant potency.Rese...

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Bibliographic Details
Main Authors: Ruth Damaris Molano, Antonello Pileggi, Hubert M Tse, Cherie L Stabler, Christopher A Fraker
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/12/2/e003897.full