A review on human cancer and potential role of MXenes in cancer therapy

Cancer is the second leading cause of death worldwide and is having a serious impact on the global economy. Various treatment modalities are in use to treat cancer but none of the techniques is risk-free. Recently, various nanomaterials such as gold, boron, and other compounds have been investigated...

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Main Authors: Rashid Bushra, Sridewi Nanthini, Anwar Ayaz, Shahabbudin Syed, Mon Aye Aye
Format: Article
Language:English
Published: EDP Sciences 2024-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/18/e3sconf_amset2024_03021.pdf
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author Rashid Bushra
Sridewi Nanthini
Anwar Ayaz
Shahabbudin Syed
Mon Aye Aye
author_facet Rashid Bushra
Sridewi Nanthini
Anwar Ayaz
Shahabbudin Syed
Mon Aye Aye
author_sort Rashid Bushra
collection DOAJ
description Cancer is the second leading cause of death worldwide and is having a serious impact on the global economy. Various treatment modalities are in use to treat cancer but none of the techniques is risk-free. Recently, various nanomaterials such as gold, boron, and other compounds have been investigated for radiotherapy and as anti-cancer drug carriers with promising results. MXenes are 2D novel nanomaterials and their biomedical and anticancer properties are gaining interest due to their high biomedical activity, less bio-toxicity, and photo-responsive nature. However, the biological properties of MXense have not been studied extensively, therefore, limited data is published on its in-vitro and in-vivo anticancer activities, drug loading efficacy, targeted release, and on its photothermal therapy response. In this review, we have discussed the use of nanoparticles and MXenen nanomaterial in cancer therapy. Furthermore, the role of Mxene as a photothermal agent and drug carrier has also been emphasized, along with the present challenges for the use of nanomaterials in the treatment of cancer.
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spelling doaj.art-a28877a0cf654b999b1e2d0613a7084f2024-02-13T08:28:16ZengEDP SciencesE3S Web of Conferences2267-12422024-01-014880302110.1051/e3sconf/202448803021e3sconf_amset2024_03021A review on human cancer and potential role of MXenes in cancer therapyRashid Bushra0Sridewi Nanthini1Anwar Ayaz2Shahabbudin Syed3Mon Aye Aye4Department of Maritime Science and Technology, Faculty of Defence Science and Technology, National Defence University of MalaysiaDepartment of Maritime Science and Technology, Faculty of Defence Science and Technology, National Defence University of MalaysiaDepartment of Biological Sciences, School of Science and Technology, Sunway UniversityDepartment of science, School of Technology, Pandit Deendayal Petroleum UniversityDepartment of Maritime Science and Technology, Faculty of Defence Science and Technology, National Defence University of MalaysiaCancer is the second leading cause of death worldwide and is having a serious impact on the global economy. Various treatment modalities are in use to treat cancer but none of the techniques is risk-free. Recently, various nanomaterials such as gold, boron, and other compounds have been investigated for radiotherapy and as anti-cancer drug carriers with promising results. MXenes are 2D novel nanomaterials and their biomedical and anticancer properties are gaining interest due to their high biomedical activity, less bio-toxicity, and photo-responsive nature. However, the biological properties of MXense have not been studied extensively, therefore, limited data is published on its in-vitro and in-vivo anticancer activities, drug loading efficacy, targeted release, and on its photothermal therapy response. In this review, we have discussed the use of nanoparticles and MXenen nanomaterial in cancer therapy. Furthermore, the role of Mxene as a photothermal agent and drug carrier has also been emphasized, along with the present challenges for the use of nanomaterials in the treatment of cancer.https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/18/e3sconf_amset2024_03021.pdf
spellingShingle Rashid Bushra
Sridewi Nanthini
Anwar Ayaz
Shahabbudin Syed
Mon Aye Aye
A review on human cancer and potential role of MXenes in cancer therapy
E3S Web of Conferences
title A review on human cancer and potential role of MXenes in cancer therapy
title_full A review on human cancer and potential role of MXenes in cancer therapy
title_fullStr A review on human cancer and potential role of MXenes in cancer therapy
title_full_unstemmed A review on human cancer and potential role of MXenes in cancer therapy
title_short A review on human cancer and potential role of MXenes in cancer therapy
title_sort review on human cancer and potential role of mxenes in cancer therapy
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/18/e3sconf_amset2024_03021.pdf
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