Viral Population Changes during Murine Norovirus Propagation in RAW 264.7 Cells

Viral Population Changes during Murine Norovirus Propagation in RAW 264.7 Cells

Laboratory adaptation of viruses is an essential technique for basic virology research, including the generation of attenuated vaccine strains, although the principles of cell adaptation remain largely unknown. Deep sequencing of murine norovirus (MuNoV) S7 during serial passages in RAW264.7 cells s...

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Bibliographic Details
Main Authors: Takuya Kitamoto, Reiko Takai-Todaka, Akiko Kato, Kumiko Kanamori, Hirotaka Takagi, Kazuhiro Yoshida, Kazuhiko Katayama, Akira Nakanishi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Microbiology
Subjects:
norovirus
RAW264.7 cells
cell adaptation
mouse
Calicivirus
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01091/full

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