Retinal dysfunction in Huntington’s disease mouse models concurs with local gliosis and microglia activation

Retinal dysfunction in Huntington’s disease mouse models concurs with local gliosis and microglia activation

Abstract Huntington’s disease (HD) is caused by an aberrant expansion of CAG repeats in the HTT gene that mainly affects basal ganglia. Although striatal dysfunction has been widely studied in HD mouse models, other brain areas can also be relevant to the pathology. In this sense, we have special in...

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Hlavní autoři: Fátima Cano-Cano, Francisco Martín-Loro, Andrea Gallardo-Orihuela, María del Carmen González-Montelongo, Samanta Ortuño-Miquel, Irati Hervás-Corpión, Pedro de la Villa, Lucía Ramón-Marco, Jorge Navarro-Calvo, Laura Gómez-Jaramillo, Ana I. Arroba, Luis M. Valor
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2024-02-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-024-54347-8

Internet

https://doi.org/10.1038/s41598-024-54347-8

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