Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system

Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system

Objective(s): Mammals have limited limb regeneration compared to amphibians. The role of Wnt signaling pathways in limb regeneration has rarely been studied. So, this study aimed to investigate the effect of Wnt-signaling using chemicals CHIR99021 and IWP-2 on amputated mice digit tips regeneration...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Leila Taghiyar, Fatemeh Bijarchian, Mohamadreza Baghban Eslaminejad, Mahshad Doraj
Ձևաչափ:	Հոդված
Լեզու:	English
Հրապարակվել է:	Mashhad University of Medical Sciences 2024-10-01
Շարք:	Iranian Journal of Basic Medical Sciences
Խորագրեր:	bone formation organ culture proliferation regeneration wnt signaling pathway
Առցանց հասանելիություն:	https://ijbms.mums.ac.ir/article_24459_a5eb689e053f9d0426d4725607371c25.pdf

Նմանատիպ նյութեր

CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism
‌: Yingying Han, և այլն
Հրապարակվել է: (2023-02-01)

In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides)
‌: Ziqiang Feng, և այլն
Հրապարակվել է: (2022-05-01)

A Highly Selective GSK-3β Inhibitor CHIR99021 Promotes Osteogenesis by Activating Canonical and Autophagy-Mediated Wnt Signaling
‌: Bo Wang, և այլն
Հրապարակվել է: (2022-07-01)

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells
‌: Caixia Jin, և այլն
Հրապարակվել է: (2018-12-01)

In ovo injection of CHIR-99021 promotes feather follicles development via activating Wnt/β-catenin signaling pathway during chick embryonic period
‌: Ziqiang Feng, և այլն
Հրապարակվել է: (2022-06-01)

M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system
‌: Fatemeh Bijarchian, և այլն
Հրապարակվել է: (2021-11-01)

Enhanced reno-protective effects of CHIR99021 modified mesenchymal stem cells against rat acute kidney injury model
‌: Rakhshinda Habib, և այլն
Հրապարակվել է: (2024-11-01)

Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
‌: Bing Xu, և այլն
Հրապարակվել է: (2022-06-01)

Establishing stable and highly osteogenic hiPSC-derived MSCs for 3D-printed bone graft through microenvironment modulation by CHIR99021-treated osteocytes
‌: Qiuling Guo, և այլն
Հրապարակվել է: (2024-06-01)

PRI-724 and IWP-O1 Wnt Signaling Pathway Inhibitors Modulate the Expression of Glycolytic Enzymes in Tongue Cancer Cell Lines
‌: Robert Kleszcz, և այլն
Հրապարակվել է: (2023-11-01)

The roles of Notch3 on the cell proliferation and apoptosis induced by CHIR99021 in NSCLC cell lines: a functional link between Wnt and Notch signaling pathways.
‌: Chunyan Li, և այլն
Հրապարակվել է: (2013-01-01)

The effects of insulin–transferrin–selenium (ITS) and CHIR99021 on the development of pre-implantation human arrested embryos in vitro
‌: Narges Karami, և այլն
Հրապարակվել է: (2025-02-01)

Improvement of Mouse Parthenogenetic Blastocyst as Primary Colony Source of Parthenogenetic Embryonic Stem Cell (pESC) using CHIR99021
‌: Budiono, Dwi, և այլն
Հրապարակվել է: (2022)

Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
‌: Sabina Wischin, և այլն
Հրապարակվել է: (2017-04-01)

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration
‌: Delepine, Chloe, և այլն
Հրապարակվել է: (2021)

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration.
‌: Chloe Delepine, և այլն
Հրապարակվել է: (2021-01-01)

Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis
‌: Xiao‐Xu Qiu, և այլն
Հրապարակվել է: (2017-10-01)

Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
‌: Shoudong Ye, և այլն
Հրապարակվել է: (2012-01-01)

Extracellular vesicles derived from Msh homeobox 1 (Msx1)-overexpressing mesenchymal stem cells improve digit tip regeneration in an amputee mice model
‌: Sahar Shemshadi, և այլն
Հրապարակվել է: (2024-10-01)

WNT5B in Physiology and Disease
‌: Sarocha Suthon, և այլն
Հրապարակվել է: (2021-05-01)

5-Aza-2′-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells
‌: Alain Aguirre-Vázquez, և այլն
Հրապարակվել է: (2021-03-01)

Corrigendum: WNT5B in Physiology and Disease
‌: Sarocha Suthon, և այլն
Հրապարակվել է: (2021-07-01)

Wnt-5A/B Signaling in Hematopoiesis throughout Life
‌: Marina Mastelaro de Rezende, և այլն
Հրապարակվել է: (2020-07-01)

CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells.
‌: Zhiying Ai, և այլն
Հրապարակվել է: (2016-01-01)

Wnt Signaling in Atherosclerosis: Mechanisms to Therapeutic Implications
‌: Rizwana Afroz, և այլն
Հրապարակվել է: (2024-01-01)

The role of WNT10B in physiology and disease: A 10-year update
‌: Rachel S. Perkins, և այլն
Հրապարակվել է: (2023-02-01)

WNT Signaling in Hematological Malignancies
‌: Michela Frenquelli, և այլն
Հրապարակվել է: (2020-12-01)

Decoding Dishevelled-Mediated Wnt Signaling in Vertebrate Early Development
‌: De-Li Shi
Հրապարակվել է: (2020-09-01)

WNT signaling at the intersection between neurogenesis and brain tumorigenesis
‌: Maisa I. Alkailani, և այլն
Հրապարակվել է: (2022-10-01)

Wnt Signaling Coordinates the Expression of Limb Patterning Genes During Axolotl Forelimb Development and Regeneration
‌: Alexander M. Lovely, և այլն
Հրապարակվել է: (2022-04-01)

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis
‌: Benoit Vanhollebeke, և այլն
Հրապարակվել է: (2015-06-01)

Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role
‌: Irina Giralt, և այլն
Հրապարակվել է: (2021-08-01)

Mesenchymal Stem Cell Isolation from the Removed Medium of Rat’s Bone Marrow Primary Culture and their Differentiation into Skeletal Cell Lineages
‌: Mohamadreza Baghaban Eslaminejad, և այլն
Հրապարակվել է: (2008-01-01)

Co-Culture of Mesenchymal Stem Cells with Mature Chondrocytes: Producing Cartilage Construct for Application in Cartilage Regeneration
‌: Mohamadreza Baghaban Eslaminejad, և այլն
Հրապարակվել է: (2009-12-01)

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways
‌: Xuming Zhu, և այլն
Հրապարակվել է: (2023-03-01)

Canonical Wnt signaling and the regulation of divergent mesenchymal Fgf8 expression in axolotl limb development and regeneration
‌: Giacomo L Glotzer, և այլն
Հրապարակվել է: (2022-05-01)

Tumor specificity of WNT ligands and receptors reveals universal squamous cell carcinoma oncogenes
‌: Cheng Chen, և այլն
Հրապարակվել է: (2022-07-01)

Wnt Signaling in Brain Tumors: A Challenging Therapeutic Target
‌: Lorenzo Manfreda, և այլն
Հրապարակվել է: (2023-05-01)

WNT8B as an Independent Prognostic Marker for Nasopharyngeal Carcinoma
‌: Chawalit Ngernsombat, և այլն
Հրապարակվել է: (2021-07-01)

Emerging Roles of Wnt Ligands in Human Colorectal Cancer
‌: Xiaobo Nie, և այլն
Հրապարակվել է: (2020-08-01)