Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system

Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system

Objective(s): Mammals have limited limb regeneration compared to amphibians. The role of Wnt signaling pathways in limb regeneration has rarely been studied. So, this study aimed to investigate the effect of Wnt-signaling using chemicals CHIR99021 and IWP-2 on amputated mice digit tips regeneration...

書目詳細資料
Main Authors:	Leila Taghiyar, Fatemeh Bijarchian, Mohamadreza Baghban Eslaminejad, Mahshad Doraj
格式:	Article
語言:	English
出版:	Mashhad University of Medical Sciences 2024-10-01
叢編:	Iranian Journal of Basic Medical Sciences
主題:	bone formation organ culture proliferation regeneration wnt signaling pathway
在線閱讀:	https://ijbms.mums.ac.ir/article_24459_a5eb689e053f9d0426d4725607371c25.pdf

相似書籍

CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism
由: Yingying Han, et al.
出版: (2023-02-01)

In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides)
由: Ziqiang Feng, et al.
出版: (2022-05-01)

A Highly Selective GSK-3β Inhibitor CHIR99021 Promotes Osteogenesis by Activating Canonical and Autophagy-Mediated Wnt Signaling
由: Bo Wang, et al.
出版: (2022-07-01)

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells
由: Caixia Jin, et al.
出版: (2018-12-01)

In ovo injection of CHIR-99021 promotes feather follicles development via activating Wnt/β-catenin signaling pathway during chick embryonic period
由: Ziqiang Feng, et al.
出版: (2022-06-01)

M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system
由: Fatemeh Bijarchian, et al.
出版: (2021-11-01)

Enhanced reno-protective effects of CHIR99021 modified mesenchymal stem cells against rat acute kidney injury model
由: Rakhshinda Habib, et al.
出版: (2024-11-01)

Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
由: Bing Xu, et al.
出版: (2022-06-01)

Establishing stable and highly osteogenic hiPSC-derived MSCs for 3D-printed bone graft through microenvironment modulation by CHIR99021-treated osteocytes
由: Qiuling Guo, et al.
出版: (2024-06-01)

PRI-724 and IWP-O1 Wnt Signaling Pathway Inhibitors Modulate the Expression of Glycolytic Enzymes in Tongue Cancer Cell Lines
由: Robert Kleszcz, et al.
出版: (2023-11-01)

The roles of Notch3 on the cell proliferation and apoptosis induced by CHIR99021 in NSCLC cell lines: a functional link between Wnt and Notch signaling pathways.
由: Chunyan Li, et al.
出版: (2013-01-01)

The effects of insulin–transferrin–selenium (ITS) and CHIR99021 on the development of pre-implantation human arrested embryos in vitro
由: Narges Karami, et al.
出版: (2025-02-01)

Improvement of Mouse Parthenogenetic Blastocyst as Primary Colony Source of Parthenogenetic Embryonic Stem Cell (pESC) using CHIR99021
由: Budiono, Dwi, et al.
出版: (2022)

Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
由: Sabina Wischin, et al.
出版: (2017-04-01)

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration
由: Delepine, Chloe, et al.
出版: (2021)

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration.
由: Chloe Delepine, et al.
出版: (2021-01-01)

Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis
由: Xiao‐Xu Qiu, et al.
出版: (2017-10-01)

Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
由: Shoudong Ye, et al.
出版: (2012-01-01)

Extracellular vesicles derived from Msh homeobox 1 (Msx1)-overexpressing mesenchymal stem cells improve digit tip regeneration in an amputee mice model
由: Sahar Shemshadi, et al.
出版: (2024-10-01)

WNT5B in Physiology and Disease
由: Sarocha Suthon, et al.
出版: (2021-05-01)

5-Aza-2′-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells
由: Alain Aguirre-Vázquez, et al.
出版: (2021-03-01)

Corrigendum: WNT5B in Physiology and Disease
由: Sarocha Suthon, et al.
出版: (2021-07-01)

Wnt-5A/B Signaling in Hematopoiesis throughout Life
由: Marina Mastelaro de Rezende, et al.
出版: (2020-07-01)

CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells.
由: Zhiying Ai, et al.
出版: (2016-01-01)

Wnt Signaling in Atherosclerosis: Mechanisms to Therapeutic Implications
由: Rizwana Afroz, et al.
出版: (2024-01-01)

The role of WNT10B in physiology and disease: A 10-year update
由: Rachel S. Perkins, et al.
出版: (2023-02-01)

WNT Signaling in Hematological Malignancies
由: Michela Frenquelli, et al.
出版: (2020-12-01)

Decoding Dishevelled-Mediated Wnt Signaling in Vertebrate Early Development
由: De-Li Shi
出版: (2020-09-01)

WNT signaling at the intersection between neurogenesis and brain tumorigenesis
由: Maisa I. Alkailani, et al.
出版: (2022-10-01)

Wnt Signaling Coordinates the Expression of Limb Patterning Genes During Axolotl Forelimb Development and Regeneration
由: Alexander M. Lovely, et al.
出版: (2022-04-01)

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis
由: Benoit Vanhollebeke, et al.
出版: (2015-06-01)

Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role
由: Irina Giralt, et al.
出版: (2021-08-01)

Mesenchymal Stem Cell Isolation from the Removed Medium of Rat’s Bone Marrow Primary Culture and their Differentiation into Skeletal Cell Lineages
由: Mohamadreza Baghaban Eslaminejad, et al.
出版: (2008-01-01)

Co-Culture of Mesenchymal Stem Cells with Mature Chondrocytes: Producing Cartilage Construct for Application in Cartilage Regeneration
由: Mohamadreza Baghaban Eslaminejad, et al.
出版: (2009-12-01)

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways
由: Xuming Zhu, et al.
出版: (2023-03-01)

Canonical Wnt signaling and the regulation of divergent mesenchymal Fgf8 expression in axolotl limb development and regeneration
由: Giacomo L Glotzer, et al.
出版: (2022-05-01)

Tumor specificity of WNT ligands and receptors reveals universal squamous cell carcinoma oncogenes
由: Cheng Chen, et al.
出版: (2022-07-01)

Wnt Signaling in Brain Tumors: A Challenging Therapeutic Target
由: Lorenzo Manfreda, et al.
出版: (2023-05-01)

WNT8B as an Independent Prognostic Marker for Nasopharyngeal Carcinoma
由: Chawalit Ngernsombat, et al.
出版: (2021-07-01)

Emerging Roles of Wnt Ligands in Human Colorectal Cancer
由: Xiaobo Nie, et al.
出版: (2020-08-01)