Indirect markers of glomerular filtration rate in dogs and cats: a review
Early diagnosis of kidney disease continues to be a subject of intense interest. Direct measurement of glomerular filtration rate is too complicated for first-line practices; thus, indirect markers of renal function have also been evaluated. Creatinine, traditionally measured as a readout of renal f...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2018-09-01
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| Series: | Veterinární Medicína |
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| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-201809-0001_indirect-markers-of-glomerular-filtration-rate-in-dogs-and-cats-a-review.php |
| _version_ | 1828006605882392576 |
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| author | S. Kovarikova |
| author_facet | S. Kovarikova |
| author_sort | S. Kovarikova |
| collection | DOAJ |
| description | Early diagnosis of kidney disease continues to be a subject of intense interest. Direct measurement of glomerular filtration rate is too complicated for first-line practices; thus, indirect markers of renal function have also been evaluated. Creatinine, traditionally measured as a readout of renal function, has limitations in its sensitivity. In dogs and cats, cystatin C became popular approximately 15 years ago, but recent reports question its usefulness, especially in cats. Symmetric dimethylarginine seems to be very promising as a marker of glomerular filtration rate with the ability to detect renal impairment earlier than creatinine. This article presents current knowledge of qualities, limitations, advantages and availability of novel and traditionally used biomarkers of glomerular filtration rate in dogs and cats. |
| first_indexed | 2024-04-10T07:58:48Z |
| format | Article |
| id | doaj.art-a29515c82cf546bb80d340364773d62f |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T07:58:48Z |
| publishDate | 2018-09-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-a29515c82cf546bb80d340364773d62f2023-02-23T03:50:47ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922018-09-0163939541210.17221/77/2017-VETMEDvet-201809-0001Indirect markers of glomerular filtration rate in dogs and cats: a reviewS. Kovarikova0Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech RepublicEarly diagnosis of kidney disease continues to be a subject of intense interest. Direct measurement of glomerular filtration rate is too complicated for first-line practices; thus, indirect markers of renal function have also been evaluated. Creatinine, traditionally measured as a readout of renal function, has limitations in its sensitivity. In dogs and cats, cystatin C became popular approximately 15 years ago, but recent reports question its usefulness, especially in cats. Symmetric dimethylarginine seems to be very promising as a marker of glomerular filtration rate with the ability to detect renal impairment earlier than creatinine. This article presents current knowledge of qualities, limitations, advantages and availability of novel and traditionally used biomarkers of glomerular filtration rate in dogs and cats.https://vetmed.agriculturejournals.cz/artkey/vet-201809-0001_indirect-markers-of-glomerular-filtration-rate-in-dogs-and-cats-a-review.phpcreatininesdmacystatin ckidney diseasefelinecaninedogcat |
| spellingShingle | S. Kovarikova Indirect markers of glomerular filtration rate in dogs and cats: a review Veterinární Medicína creatinine sdma cystatin c kidney disease feline canine dog cat |
| title | Indirect markers of glomerular filtration rate in dogs and cats: a review |
| title_full | Indirect markers of glomerular filtration rate in dogs and cats: a review |
| title_fullStr | Indirect markers of glomerular filtration rate in dogs and cats: a review |
| title_full_unstemmed | Indirect markers of glomerular filtration rate in dogs and cats: a review |
| title_short | Indirect markers of glomerular filtration rate in dogs and cats: a review |
| title_sort | indirect markers of glomerular filtration rate in dogs and cats a review |
| topic | creatinine sdma cystatin c kidney disease feline canine dog cat |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-201809-0001_indirect-markers-of-glomerular-filtration-rate-in-dogs-and-cats-a-review.php |
| work_keys_str_mv | AT skovarikova indirectmarkersofglomerularfiltrationrateindogsandcatsareview |