Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review
In the last few decades, scientific evidence has stressed the importance of plants in the prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age-associated disorders. <i>Juglans regia</i> L. is a traditional plant that has been integrated into traditi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/12/3/604 |
| _version_ | 1797613802334715904 |
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| author | Letiția Mateș Marius Emil Rusu Daniela-Saveta Popa |
| author_facet | Letiția Mateș Marius Emil Rusu Daniela-Saveta Popa |
| author_sort | Letiția Mateș |
| collection | DOAJ |
| description | In the last few decades, scientific evidence has stressed the importance of plants in the prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age-associated disorders. <i>Juglans regia</i> L. is a traditional plant that has been integrated into traditional medicine since ancient times. Due to the presence of biologically active compounds, walnut was used in the treatment of various maladies. Recently, investigations have focused on the walnut by-products and waste products, with research on their valuable constituents and active properties. Among these secondary products, walnut septum was analyzed in several studies, its phytochemical profile described, and some of the biological activities examined. However, compared to other walnut by-products, no comprehensive review to gather all the pertinent scientific knowledge was found in the literature. Therefore, the aim of this study was to critically assess the information furnished by peer-reviewed articles regarding the walnut septum chemical composition and the related biological activities, including antioxidant activities, anti-inflammatory effects, antimicrobial properties, antidiabetic activities, anti-tumor properties, and anti-aging potential. In conclusion, as these preclinical studies showed that walnut septum metabolites were responsible for a wide range of preventive and therapeutic uses, further research should confirm the beneficial outcomes in clinical trials. |
| first_indexed | 2024-03-11T07:00:47Z |
| format | Article |
| id | doaj.art-a29eacebf51e486389bb75d46a6d1974 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T07:00:47Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-a29eacebf51e486389bb75d46a6d19742023-11-17T09:17:06ZengMDPI AGAntioxidants2076-39212023-03-0112360410.3390/antiox12030604Phytochemicals and Biological Activities of Walnut Septum: A Systematic ReviewLetiția Mateș0Marius Emil Rusu1Daniela-Saveta Popa2Department of Toxicology, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaDepartment of Toxicology, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaIn the last few decades, scientific evidence has stressed the importance of plants in the prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age-associated disorders. <i>Juglans regia</i> L. is a traditional plant that has been integrated into traditional medicine since ancient times. Due to the presence of biologically active compounds, walnut was used in the treatment of various maladies. Recently, investigations have focused on the walnut by-products and waste products, with research on their valuable constituents and active properties. Among these secondary products, walnut septum was analyzed in several studies, its phytochemical profile described, and some of the biological activities examined. However, compared to other walnut by-products, no comprehensive review to gather all the pertinent scientific knowledge was found in the literature. Therefore, the aim of this study was to critically assess the information furnished by peer-reviewed articles regarding the walnut septum chemical composition and the related biological activities, including antioxidant activities, anti-inflammatory effects, antimicrobial properties, antidiabetic activities, anti-tumor properties, and anti-aging potential. In conclusion, as these preclinical studies showed that walnut septum metabolites were responsible for a wide range of preventive and therapeutic uses, further research should confirm the beneficial outcomes in clinical trials.https://www.mdpi.com/2076-3921/12/3/604walnut septumby-productsdiaphragma juglandis fructusantioxidantsanti-agingbioactive compounds |
| spellingShingle | Letiția Mateș Marius Emil Rusu Daniela-Saveta Popa Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review Antioxidants walnut septum by-products diaphragma juglandis fructus antioxidants anti-aging bioactive compounds |
| title | Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review |
| title_full | Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review |
| title_fullStr | Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review |
| title_full_unstemmed | Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review |
| title_short | Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review |
| title_sort | phytochemicals and biological activities of walnut septum a systematic review |
| topic | walnut septum by-products diaphragma juglandis fructus antioxidants anti-aging bioactive compounds |
| url | https://www.mdpi.com/2076-3921/12/3/604 |
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