The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation

Aim: to improve the results of treating patients with anastomotic biliary strictures of the bile ducts after orthotopic liver transplantation.Materials and methods. This study is based on the results of the endoscopic treatment of 36 patients with biliary complications after orthotopic liver transpl...

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Main Authors: Alexey V. Kurenkov, Yury S. Teterin, Oleg D. Olisov, Petr A. Yartsev, Murad S. Novruzbekov, Kubay M. Magomedov
Format: Article
Language:Russian
Published: Gastro LLC 2019-03-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/328
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author Alexey V. Kurenkov
Yury S. Teterin
Oleg D. Olisov
Petr A. Yartsev
Murad S. Novruzbekov
Kubay M. Magomedov
author_facet Alexey V. Kurenkov
Yury S. Teterin
Oleg D. Olisov
Petr A. Yartsev
Murad S. Novruzbekov
Kubay M. Magomedov
author_sort Alexey V. Kurenkov
collection DOAJ
description Aim: to improve the results of treating patients with anastomotic biliary strictures of the bile ducts after orthotopic liver transplantation.Materials and methods. This study is based on the results of the endoscopic treatment of 36 patients with biliary complications after orthotopic liver transplantation, who were admitted to the N.V. Sklifosovsky Research Institute for Emergency Medicine from December 2001 to December 2017. The endoscopic treatment program included diagnostic ERCP, endoscopic papillosphincterotomy (EPST), bilioduodenal stenting, nasobiliary drainage, balloon dilatation.Results. Against the background of the staged endoscopic treatment, the stable remission of anastomotic biliary strictures (ABS) was achieved in 17 (53.1 %) patients, with 4 of them (12.5 %) showing a successfully resolved insufficiency of biliobiliary anastomosis (BBA). The average duration of endoscopic treatment was 12 ± 1.9 months. The number of ERCPs performed for each patient varied from 1 to 12 and averaged 3. In the majority of patients (75 %) who received one or more courses of endoscopic treatment, a successful correction of anastomotic strictures with no recurrence within 2–5 years was achieved.Conclusion. Staged endoscopic treatment is established to be highly effective in patients with anastomotic biliary strictures and the insufficiency of bilobiliary anastomoses occurred after orthotopic liver transplantation. Such a treatment allows good long-term results to be achieved by a minimally invasive method.
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spelling doaj.art-a2a2949121f24d08be9983aea60ada392024-03-25T16:53:08ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732019-03-01291626710.22416/1382-4376-2019-29-1-62-67286The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver TransplantationAlexey V. Kurenkov0Yury S. Teterin1Oleg D. Olisov2Petr A. Yartsev3Murad S. Novruzbekov4Kubay M. Magomedov5N.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineAim: to improve the results of treating patients with anastomotic biliary strictures of the bile ducts after orthotopic liver transplantation.Materials and methods. This study is based on the results of the endoscopic treatment of 36 patients with biliary complications after orthotopic liver transplantation, who were admitted to the N.V. Sklifosovsky Research Institute for Emergency Medicine from December 2001 to December 2017. The endoscopic treatment program included diagnostic ERCP, endoscopic papillosphincterotomy (EPST), bilioduodenal stenting, nasobiliary drainage, balloon dilatation.Results. Against the background of the staged endoscopic treatment, the stable remission of anastomotic biliary strictures (ABS) was achieved in 17 (53.1 %) patients, with 4 of them (12.5 %) showing a successfully resolved insufficiency of biliobiliary anastomosis (BBA). The average duration of endoscopic treatment was 12 ± 1.9 months. The number of ERCPs performed for each patient varied from 1 to 12 and averaged 3. In the majority of patients (75 %) who received one or more courses of endoscopic treatment, a successful correction of anastomotic strictures with no recurrence within 2–5 years was achieved.Conclusion. Staged endoscopic treatment is established to be highly effective in patients with anastomotic biliary strictures and the insufficiency of bilobiliary anastomoses occurred after orthotopic liver transplantation. Such a treatment allows good long-term results to be achieved by a minimally invasive method.https://www.gastro-j.ru/jour/article/view/328orthotopic liver transplantationbiliary complicationsanastomotic strictureinsufficiency of biliary anastomosesbilioduodenal stentingendoscopic retrograde cholangiography
spellingShingle Alexey V. Kurenkov
Yury S. Teterin
Oleg D. Olisov
Petr A. Yartsev
Murad S. Novruzbekov
Kubay M. Magomedov
The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
orthotopic liver transplantation
biliary complications
anastomotic stricture
insufficiency of biliary anastomoses
bilioduodenal stenting
endoscopic retrograde cholangiography
title The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
title_full The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
title_fullStr The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
title_full_unstemmed The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
title_short The Role of Endoscopy in the Treatment of Biliary Complications after Orthotopic Liver Transplantation
title_sort role of endoscopy in the treatment of biliary complications after orthotopic liver transplantation
topic orthotopic liver transplantation
biliary complications
anastomotic stricture
insufficiency of biliary anastomoses
bilioduodenal stenting
endoscopic retrograde cholangiography
url https://www.gastro-j.ru/jour/article/view/328
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