Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan
Background: In recent years, the world has faced with the COVID-19 pandemic, followed by a significant increase in the use of antibiotics to control the COVID-19 and other secondary infections. The nonbiodegradable characteristics of antibiotics and their residues in the environment leads to incre...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Kerman University of Medical Sciences
2022-08-01
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| Series: | Environmental Health Engineering and Management |
| Subjects: | |
| Online Access: | http://ehemj.com/article-1-981-en.html |
| _version_ | 1798031824776069120 |
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| author | Mehri Samandari Hossein Movahedian Attar Karim Ebrahimpour Farzaneh Mohammadi Soudabeh Ghodsi |
| author_facet | Mehri Samandari Hossein Movahedian Attar Karim Ebrahimpour Farzaneh Mohammadi Soudabeh Ghodsi |
| author_sort | Mehri Samandari |
| collection | DOAJ |
| description | Background: In recent years, the world has faced with the COVID-19 pandemic, followed by a significant
increase in the use of antibiotics to control the COVID-19 and other secondary infections. The nonbiodegradable
characteristics of antibiotics and their residues in the environment leads to increased
microbial and drug resistance. Therefore, due to the high importance of antibiotics, two antibiotics,
ampicillin and penicillin G, were studied in Isfahan municipal wastewater treatment plants (WWTPs).
Methods: Sampling was performed for two months during 13 sampling periods and antibiotics were
measured using high-performance liquid chromatography with UV detector (HPLC/UV) instrument.
Results: Ampicillin and penicillin G were identified in all samples taken from the both WWTPs. The
average concentration of penicillin G in WWTP E and S at the influent, effluent and its removal efficiency
were 1050.54 ± 761.43 μg/L, 52.89 ± 49.27 μg/L, 89.80 ± 19.42%, 2055.12 ± 1788.08 μg/L, 143.01 ± 162.59
μg/L and 82.76 ± 21.85%, respectively. Also, the average concentration of ampicillin in WWTP E and S in
the influent (796.44 ± 809.6 and 447.1 ± 322.39 μg/L), effluent (48.94 ± 24.25 and 90.31 ± 75.91 μg/L), and
its removal efficiency (86.22 ± 19.84% and 66.85 ± 24.88%) were determined.
Conclusion: In two studied WWTPs, the concentration of antibiotics was higher during the COVID-19
pandemic in comparison with previous studies. The statistical analysis showed that there was no significant
relationship between the concentration of antibiotics in WWTPs (P < 0.05). Also, the statistical results
indicated that the correlation is not significant between removal efficiency of antibiotics and removal
efficiency of wastewater main parameters. |
| first_indexed | 2024-04-11T20:02:45Z |
| format | Article |
| id | doaj.art-a2a2d8adc5a1467fb5d2755633880c20 |
| institution | Directory Open Access Journal |
| issn | 2423-3765 2423-4311 |
| language | English |
| last_indexed | 2024-04-11T20:02:45Z |
| publishDate | 2022-08-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Environmental Health Engineering and Management |
| spelling | doaj.art-a2a2d8adc5a1467fb5d2755633880c202022-12-22T04:05:31ZengKerman University of Medical SciencesEnvironmental Health Engineering and Management2423-37652423-43112022-08-019320121110.34172/EHEM.2022.21Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in IsfahanMehri Samandari0Hossein Movahedian Attar1Karim Ebrahimpour2Farzaneh Mohammadi3Soudabeh Ghodsi4Student Research Committee, School of Health, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, IranStudent Research Committee, School of Health, Isfahan University of Medical Sciences, Isfahan, IranBackground: In recent years, the world has faced with the COVID-19 pandemic, followed by a significant increase in the use of antibiotics to control the COVID-19 and other secondary infections. The nonbiodegradable characteristics of antibiotics and their residues in the environment leads to increased microbial and drug resistance. Therefore, due to the high importance of antibiotics, two antibiotics, ampicillin and penicillin G, were studied in Isfahan municipal wastewater treatment plants (WWTPs). Methods: Sampling was performed for two months during 13 sampling periods and antibiotics were measured using high-performance liquid chromatography with UV detector (HPLC/UV) instrument. Results: Ampicillin and penicillin G were identified in all samples taken from the both WWTPs. The average concentration of penicillin G in WWTP E and S at the influent, effluent and its removal efficiency were 1050.54 ± 761.43 μg/L, 52.89 ± 49.27 μg/L, 89.80 ± 19.42%, 2055.12 ± 1788.08 μg/L, 143.01 ± 162.59 μg/L and 82.76 ± 21.85%, respectively. Also, the average concentration of ampicillin in WWTP E and S in the influent (796.44 ± 809.6 and 447.1 ± 322.39 μg/L), effluent (48.94 ± 24.25 and 90.31 ± 75.91 μg/L), and its removal efficiency (86.22 ± 19.84% and 66.85 ± 24.88%) were determined. Conclusion: In two studied WWTPs, the concentration of antibiotics was higher during the COVID-19 pandemic in comparison with previous studies. The statistical analysis showed that there was no significant relationship between the concentration of antibiotics in WWTPs (P < 0.05). Also, the statistical results indicated that the correlation is not significant between removal efficiency of antibiotics and removal efficiency of wastewater main parameters.http://ehemj.com/article-1-981-en.htmlanti-bacterial agentscovid-19wastewaterhigh-pressure liquid chromatographyampicillinpenicillin g |
| spellingShingle | Mehri Samandari Hossein Movahedian Attar Karim Ebrahimpour Farzaneh Mohammadi Soudabeh Ghodsi Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan Environmental Health Engineering and Management anti-bacterial agents covid-19 wastewater high-pressure liquid chromatography ampicillin penicillin g |
| title | Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan |
| title_full | Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan |
| title_fullStr | Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan |
| title_full_unstemmed | Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan |
| title_short | Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan |
| title_sort | measurement of ampicillin and penicillin g antibiotics in wastewater treatment plants during the covid 19 pandemic a case study in isfahan |
| topic | anti-bacterial agents covid-19 wastewater high-pressure liquid chromatography ampicillin penicillin g |
| url | http://ehemj.com/article-1-981-en.html |
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