Synthetic Assembly of Mannose Moieties Using Polymer Chemistry and the Biological Evaluation of Its Interaction towards Concanavalin A

Synthetic Assembly of Mannose Moieties Using Polymer Chemistry and the Biological Evaluation of Its Interaction towards Concanavalin A

Protein–carbohydrate interactions exhibit myriad intracellular recognition events, so understanding and investigating their specific interaction with high selectivity and strength are of crucial importance. In order to examine the effect of multivalent binding on the specificity of protein–carbohydr...

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Bibliographic Details
Main Authors: Deepti Diwan, Kohei Shinkai, Toshihiro Tetsuka, Bin Cao, Hidenao Arai, Tetsuo Koyama, Ken Hatano, Koji Matsuoka
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
mannose
glycopolymers
concanavalin A
surface plasmon resonance
radical polymerization
kinetic affinity
Online Access:http://www.mdpi.com/1420-3049/22/1/157

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