Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid
It is well known that desensitization treatment with aspirin can significantly improve symptoms and quality of life in patient with aspirin-exacerbated respiratory disease. However, its mechanism has not been clearly understood yet. In this case report, 41-year-old male patient was referr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2013-12-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/485 |
| _version_ | 1818018398324391936 |
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| author | Ali Kutlu Murat Salihoglu Aptullah Haholu Enver Cesmeci Hakan Cincik Sami Ozturk |
| author_facet | Ali Kutlu Murat Salihoglu Aptullah Haholu Enver Cesmeci Hakan Cincik Sami Ozturk |
| author_sort | Ali Kutlu |
| collection | DOAJ |
| description | It is well known that desensitization treatment with aspirin can significantly improve symptoms and quality of life in patient with aspirin-exacerbated respiratory disease. However, its mechanism has not been clearly understood yet. In this case report, 41-year-old male patient was referred to our allergy and immunology department with complaints of chronic rhinosinusitis including postnasal discharge, sneezing, facial pain/pressure, waking up tired, nasal obstruction, smell loss for a long time. According to the patient, the complaints were controlled partially with nasal steroid and antihistamines, and single dose parenteral depot steroids were highly effective in controlling the symptoms and each time this effect lasted at least three weeks.
The patient was told to use aspirin when needed analgesic and he started to use aspirin 500 mg bid. po for 10 days for his pain in the joints. The patient stressed the superiority of aspirin over other drugs including oral antihistamine and LTA and its equality to systemic steroid drugs in suppressing symptoms. It seemed that aspirin had positive effects in allergic inflammation at least in some subset of aspirin tolerant patients with chronic sinusitis. |
| first_indexed | 2024-04-14T07:39:45Z |
| format | Article |
| id | doaj.art-a2a433874aaa488399751f24b1f57940 |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-04-14T07:39:45Z |
| publishDate | 2013-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-a2a433874aaa488399751f24b1f579402022-12-22T02:05:33ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492013-12-01124450Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic AcidAli Kutlu0Murat Salihoglu1Aptullah Haholu2Enver Cesmeci3Hakan Cincik4Sami Ozturk5Department of Immunulogy and Allergology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyDepartment of Otorhinolaryngology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyDepartment of Pathology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyDepartment of Otorhinolaryngology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyDepartment of Otorhinolaryngology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyDepartment of Immunulogy and Allergology, GATA Haydarpasa Training Hospital, Istanbul, TurkeyIt is well known that desensitization treatment with aspirin can significantly improve symptoms and quality of life in patient with aspirin-exacerbated respiratory disease. However, its mechanism has not been clearly understood yet. In this case report, 41-year-old male patient was referred to our allergy and immunology department with complaints of chronic rhinosinusitis including postnasal discharge, sneezing, facial pain/pressure, waking up tired, nasal obstruction, smell loss for a long time. According to the patient, the complaints were controlled partially with nasal steroid and antihistamines, and single dose parenteral depot steroids were highly effective in controlling the symptoms and each time this effect lasted at least three weeks. The patient was told to use aspirin when needed analgesic and he started to use aspirin 500 mg bid. po for 10 days for his pain in the joints. The patient stressed the superiority of aspirin over other drugs including oral antihistamine and LTA and its equality to systemic steroid drugs in suppressing symptoms. It seemed that aspirin had positive effects in allergic inflammation at least in some subset of aspirin tolerant patients with chronic sinusitis.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/485Acetylsalicylic acidAllergyAspirinChronic rhinosinusitisCorticosteroidsNasal polyps |
| spellingShingle | Ali Kutlu Murat Salihoglu Aptullah Haholu Enver Cesmeci Hakan Cincik Sami Ozturk Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid Iranian Journal of Allergy, Asthma and Immunology Acetylsalicylic acid Allergy Aspirin Chronic rhinosinusitis Corticosteroids Nasal polyps |
| title | Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid |
| title_full | Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid |
| title_fullStr | Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid |
| title_full_unstemmed | Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid |
| title_short | Short-term Beneficial Effect of Aspirin in Patient with Chronic Rhinosinusitis and Tolerant to Acetylsalicylic Acid |
| title_sort | short term beneficial effect of aspirin in patient with chronic rhinosinusitis and tolerant to acetylsalicylic acid |
| topic | Acetylsalicylic acid Allergy Aspirin Chronic rhinosinusitis Corticosteroids Nasal polyps |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/485 |
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