Inhibition of Androgen Signalling Improves the Outcomes of Therapies for Bladder Cancer: Results from a Systematic Review of Preclinical and Clinical Evidence and Meta-Analysis of Clinical Studies

Inhibition of Androgen Signalling Improves the Outcomes of Therapies for Bladder Cancer: Results from a Systematic Review of Preclinical and Clinical Evidence and Meta-Analysis of Clinical Studies

Bladder cancer (BCa) is an endocrine-related tumour and the activation of androgen signalling pathways may promote bladder tumorigenesis. We summarized the available preclinical and clinical evidence on the implications of the manipulation of androgen signalling pathways on the outcomes of BCa thera...

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Bibliographic Details
Main Authors: Massimiliano Creta, Giuseppe Celentano, Luigi Napolitano, Roberto La Rocca, Marco Capece, Gianluigi Califano, Claudia Collà Ruvolo, Francesco Mangiapia, Simone Morra, Carmine Turco, Lorenzo Spirito, Ferdinando Fusco, Ciro Imbimbo, Vincenzo Mirone, Nicola Longo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Diagnostics
Subjects:
5 alpha reductase inhibitors
androgen deprivation therapy
androgen receptor
bladder cancer
Online Access:https://www.mdpi.com/2075-4418/11/2/351

Internet

https://www.mdpi.com/2075-4418/11/2/351

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