Epithelial-Mesenchymal Transition and its Role in Renal Fibrogenesis

Abstract Renal fibrosis in chronic renal failure poses a major challenge with regard to providing specific therapeutic strategies. The current hypothesis of the epithelial-mesenchymal transition (EMT) in renal fibrosis proposes that matrix producing fibroblasts and myofibroblasts generated in the di...

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Bibliographic Details
Main Authors: Brij Mohan Kumar Singh, Mary Mathew
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2022-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132022000100330&tlng=en