Mass spectrometric investigations of the action of hypochlorous acid on monomeric and oligomeric components of glycosaminoglycans
Hypochlorous acid (HOCl) is a strong non-radical oxidant, which is generated during inflammatory processes under the catalysis of the enzyme myeloperoxidase (MPO). HOCl reacts particularly with sulfhydryl and amino acid residues but affects also many other biomolecules. For instance, the glycosamino...
Main Authors: | Jenny Leopold, Patricia Prabutzki, Ariane Nimptsch, Jürgen Schiller |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-07-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580823000298 |
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