The histone chaperone function of Daxx is dispensable for embryonic development

The histone chaperone function of Daxx is dispensable for embryonic development

Abstract Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form a protein complex that deposits H3.3 into heterochromatic regions of the genome, including centromeres, telomeres, and repeat loci. To advance...

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Bibliographic Details
Main Authors:	Chang Sun, Yuan Qi, Natalie Fowlkes, Nina Lazic, Xiaoping Su, Guillermina Lozano, Amanda R. Wasylishen
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-08-01
Series:	Cell Death and Disease
Online Access:	https://doi.org/10.1038/s41419-023-06089-0

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