Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection
AIM: To explore the feasibility, safety and effect of the full-thickness lamellar keratoplasty for the treatment of pseudomonas aeruginosa corneal ulcer. <p>METHODS: Based on a retrospective non-controlled study, 25 patients were given the full-thickness lamellar keratoplasty for clinical diag...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-02-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2015/2/201502038.pdf |
| _version_ | 1818022633375006720 |
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| author | Xin Wang Yan-Chao Wu |
| author_facet | Xin Wang Yan-Chao Wu |
| author_sort | Xin Wang |
| collection | DOAJ |
| description | AIM: To explore the feasibility, safety and effect of the full-thickness lamellar keratoplasty for the treatment of pseudomonas aeruginosa corneal ulcer. <p>METHODS: Based on a retrospective non-controlled study, 25 patients were given the full-thickness lamellar keratoplasty for clinical diagnosis of pseudomonas aeruginosa infection and corneal ulcer medication conventional anti-gram-negative bacteria. Routine follow-up were carried out at postoperative 1wk; 1, 3, 6, 12, 18mo to observe the situation of corneal epithelial healing, recurrent infection, immune rejection, graft transparency and best corrected visual acuity, <i>etc.</i> At the 6 and 12mo postoperative, corneal endothelial cell density was reexamined.<p>RESULTS: No patients because of Descemet's membrane rupture underwent penetrating keratoplasty surgery: One only in cases of bacterial infection after 1mo, once again did not cultivate a culture of bacteria pseudomonas aeruginosa, and the remaining 24 cases average follow-up 14±6mo, corneal graft were transparent, the cure rate was 96%. At the sixth month after surgery, there were 16 cases of eye surgery best corrected visual acuity ≥4.5, of which 3 cases ≥4.8. At the sixth month after surgery, the average corneal endothelial cell density 2 425±278/mm<sup>2</sup>; At 12mo postoperatively, it was 2 257± 326/mm<sup>2</sup>.<p>CONCLUSION: Full-thickness lamellar keratoplasty is an effective method of pseudomonas aeruginosa infection in the treatment of corneal ulcers, corneal drying material glycerol can be achieved by visual effects. |
| first_indexed | 2024-12-10T03:31:32Z |
| format | Article |
| id | doaj.art-a2bfda7c07b0498cb14917d011a208b9 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-10T03:31:32Z |
| publishDate | 2015-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-a2bfda7c07b0498cb14917d011a208b92022-12-22T02:03:49ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-02-0115232332510.3980/j.issn.1672-5123.2015.2.38Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infectionXin Wang0Yan-Chao Wu1Hebei Institute of Ophthalmology, Hebei Provincial Key Laboratory of Ophthalmology, Hebei Province Eye Hospital, Xingtai 054001, Hebei Province, ChinaHebei Institute of Ophthalmology, Hebei Provincial Key Laboratory of Ophthalmology, Hebei Province Eye Hospital, Xingtai 054001, Hebei Province, ChinaAIM: To explore the feasibility, safety and effect of the full-thickness lamellar keratoplasty for the treatment of pseudomonas aeruginosa corneal ulcer. <p>METHODS: Based on a retrospective non-controlled study, 25 patients were given the full-thickness lamellar keratoplasty for clinical diagnosis of pseudomonas aeruginosa infection and corneal ulcer medication conventional anti-gram-negative bacteria. Routine follow-up were carried out at postoperative 1wk; 1, 3, 6, 12, 18mo to observe the situation of corneal epithelial healing, recurrent infection, immune rejection, graft transparency and best corrected visual acuity, <i>etc.</i> At the 6 and 12mo postoperative, corneal endothelial cell density was reexamined.<p>RESULTS: No patients because of Descemet's membrane rupture underwent penetrating keratoplasty surgery: One only in cases of bacterial infection after 1mo, once again did not cultivate a culture of bacteria pseudomonas aeruginosa, and the remaining 24 cases average follow-up 14±6mo, corneal graft were transparent, the cure rate was 96%. At the sixth month after surgery, there were 16 cases of eye surgery best corrected visual acuity ≥4.5, of which 3 cases ≥4.8. At the sixth month after surgery, the average corneal endothelial cell density 2 425±278/mm<sup>2</sup>; At 12mo postoperatively, it was 2 257± 326/mm<sup>2</sup>.<p>CONCLUSION: Full-thickness lamellar keratoplasty is an effective method of pseudomonas aeruginosa infection in the treatment of corneal ulcers, corneal drying material glycerol can be achieved by visual effects.http://ies.ijo.cn/cn_publish/2015/2/201502038.pdflamellar keratoplastycorneal ulcersglycerin |
| spellingShingle | Xin Wang Yan-Chao Wu Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection Guoji Yanke Zazhi lamellar keratoplasty corneal ulcers glycerin |
| title | Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| title_full | Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| title_fullStr | Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| title_full_unstemmed | Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| title_short | Explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| title_sort | explore the full thick layer of corneal transplantation in the treatment of pseudomonas aeruginosa corneal ulcer infection |
| topic | lamellar keratoplasty corneal ulcers glycerin |
| url | http://ies.ijo.cn/cn_publish/2015/2/201502038.pdf |
| work_keys_str_mv | AT xinwang explorethefullthicklayerofcornealtransplantationinthetreatmentofpseudomonasaeruginosacornealulcerinfection AT yanchaowu explorethefullthicklayerofcornealtransplantationinthetreatmentofpseudomonasaeruginosacornealulcerinfection |