Assessments of TP53 and CTNNB1 gene hotspot mutations in circulating tumour DNA of hepatitis B virus-induced hepatocellular carcinoma

Assessments of TP53 and CTNNB1 gene hotspot mutations in circulating tumour DNA of hepatitis B virus-induced hepatocellular carcinoma

Background: Hepatitis B virus (HBV) infection is one of the major causes of chronic liver disease, which progresses from chronic hepatitis B (CHB) to fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Early detection and laboratory-based screening of hepatocellular carcinoma are still major ch...

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Bibliographic Details
Main Authors: Sonu Kumar, Neeti Nadda, Afnan Quadri, Rahul Kumar, Shashi Paul, Pranay Tanwar, Shivanand Gamanagatti, Nihar Ranjan Dash, Anoop Saraya, Shalimar, Baibaswata Nayak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
HBV
HCC
CtDNA
ddPCR
driver mutation
circulatory tumor DNA (ctDNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1235260/full

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