Genomic profiling and associated B cell lineages delineate the efficacy of neoadjuvant anti-PD-1-based therapy in oesophageal squamous cell carcinomaResearch in context

Genomic profiling and associated B cell lineages delineate the efficacy of neoadjuvant anti-PD-1-based therapy in oesophageal squamous cell carcinomaResearch in context

Summary: Background: Neoadjuvant chemoimmunotherapy has offered novel therapeutic options for patients with locally advanced oesophageal squamous cell carcinoma (ESCC). Depicting the landscape of genomic and immune profiles is critical in predicting therapeutic responses. Methods: We integrated who...

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Bibliographic Details
Main Authors: Hongyu Zhang, Haoyu Wen, Qiaoliang Zhu, Yuchen Zhang, Fengkai Xu, Teng Ma, Yifan Guo, Chunlai Lu, Xuelian Zhao, Yuan Ji, Zhiqiang Wang, Yiwei Chu, Di Ge, Jie Gu, Ronghua Liu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:EBioMedicine
Subjects:
Oesophageal squamous cell carcinoma
Immunotherapy
B cells
MMR
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424000069

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