NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions

NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions

Exosomes are membranous vesicles actively secreted by almost all cells and they deliver certain intracellular molecules, including nucleic acids, proteins, and lipids, to target cells. They are also considered to be good carriers for drug delivery due to their biocompatibility, high permeability, lo...

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Bibliographic Details
Main Authors: Heyong Luo, Yanhua Zhou, Jing Zhang, Yingchun Zhang, Shiqi Long, Xiaojin Lin, Anqing Yang, Jiangyao Duan, Na Yang, Zhiru Yang, Qiyuan Che, Yuxin Yang, Ting Guo, Dan Zi, Weiwei Ouyang, Wei Yang, Zhu Zeng, Xing Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
ovarian cancer
exosomes
natural killer cells
cisplatin
immunomodulatory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1087689/full

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