ABPS: An R Package for Calculating the Abnormal Blood Profile Score

The Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ab...

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Main Authors: Frédéric Schütz, Alix Zollinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01638/full
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author Frédéric Schütz
Frédéric Schütz
Alix Zollinger
author_facet Frédéric Schütz
Frédéric Schütz
Alix Zollinger
author_sort Frédéric Schütz
collection DOAJ
description The Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ability to identify doping than each parameter taken alone. The resulting score allows the detection of several types of doping using a single score and is part of the current Athlete Biological Passport program managed by World Anti-Doping Agency (WADA). We describe ≪ ABPS ≫, an R package that allows the calculation of this score. This is the first software implementation calculating this score that is released publicly. The package also contains functions to calculate the OFF-score (another score used for detection of doping), as well as several test datasets. The package is useful for laboratories conducting anti-doping analyses and for researchers working on anti-doping research projects. In particular, it has been successfully used in projects estimating the prevalence of blood doping.
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spelling doaj.art-a2c5c10ed9a5489dbb1013deca04625b2022-12-21T22:58:49ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2018-11-01910.3389/fphys.2018.01638358252ABPS: An R Package for Calculating the Abnormal Blood Profile ScoreFrédéric Schütz0Frédéric Schütz1Alix Zollinger2Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, SwitzerlandCenter for Integrative Genomics, University of Lausanne, Lausanne, SwitzerlandBioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, SwitzerlandThe Abnormal Blood Profile Score (ABPS) is used to identify blood doping in sport. It combines seven hematological markers, including hemoglobin level, reticulocytes percent, and haematocrit level, using two different machine learning algorithms in order to create a single score that has a better ability to identify doping than each parameter taken alone. The resulting score allows the detection of several types of doping using a single score and is part of the current Athlete Biological Passport program managed by World Anti-Doping Agency (WADA). We describe ≪ ABPS ≫, an R package that allows the calculation of this score. This is the first software implementation calculating this score that is released publicly. The package also contains functions to calculate the OFF-score (another score used for detection of doping), as well as several test datasets. The package is useful for laboratories conducting anti-doping analyses and for researchers working on anti-doping research projects. In particular, it has been successfully used in projects estimating the prevalence of blood doping.https://www.frontiersin.org/article/10.3389/fphys.2018.01638/fullcode:Ranti-dopingABPSblood dopingmachine learning
spellingShingle Frédéric Schütz
Frédéric Schütz
Alix Zollinger
ABPS: An R Package for Calculating the Abnormal Blood Profile Score
Frontiers in Physiology
code:R
anti-doping
ABPS
blood doping
machine learning
title ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_full ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_fullStr ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_full_unstemmed ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_short ABPS: An R Package for Calculating the Abnormal Blood Profile Score
title_sort abps an r package for calculating the abnormal blood profile score
topic code:R
anti-doping
ABPS
blood doping
machine learning
url https://www.frontiersin.org/article/10.3389/fphys.2018.01638/full
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