Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

Human herpesvirus 8 (HHV-8) is an oncogenic virus that enters cells by fusion of the viral and endosomal cellular membranes in a process mediated by viral surface glycoproteins. One of the cellular receptors hijacked by HHV-8 to gain access to cells is the EphA2 tyrosine kinase receptor, and the mec...

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Manylion Llyfryddiaeth
Prif Awduron: Taylor P Light, Delphine Brun, Pablo Guardado-Calvo, Riccardo Pederzoli, Ahmed Haouz, Frank Neipel, Félix A Rey, Kalina Hristova, Marija Backovic
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2021-09-01
Cyfres:PLoS Biology
Mynediad Ar-lein:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001392&type=printable