The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies
Tomato (<i>Solanum lycopersicum</i> L.) is a model system for studying the molecular basis of resistance in plants. The investigation of evolutionary dynamics of tomato resistance (R)-loci provides unique opportunities for identifying factors that promote or constrain genome evolution. N...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/12/2/184 |
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| author | Giuseppe Andolfo Nunzio D’Agostino Luigi Frusciante Maria Raffaella Ercolano |
| author_facet | Giuseppe Andolfo Nunzio D’Agostino Luigi Frusciante Maria Raffaella Ercolano |
| author_sort | Giuseppe Andolfo |
| collection | DOAJ |
| description | Tomato (<i>Solanum lycopersicum</i> L.) is a model system for studying the molecular basis of resistance in plants. The investigation of evolutionary dynamics of tomato resistance (R)-loci provides unique opportunities for identifying factors that promote or constrain genome evolution. Nucleotide-binding domain and leucine-rich repeat (NB-LRR) receptors belong to one of the most plastic and diversified families. The vast amount of genomic data available for Solanaceae and wild tomato relatives provides unprecedented insights into the patterns and mechanisms of evolution of NB-LRR genes. Comparative analysis remarked a reshuffling of R-islands on chromosomes and a high degree of adaptive diversification in key R-loci induced by species-specific pathogen pressure. Unveiling NB-LRR natural variation in tomato and in other Solanaceae species offers the opportunity to effectively exploit genetic diversity in genomic-driven breeding programs with the aim of identifying and introducing new resistances in tomato cultivars. Within this motivating context, we reviewed the repertoire of NB-LRR genes available for tomato improvement with a special focus on signatures of adaptive processes. This issue is still relevant and not thoroughly investigated. We believe that the discovery of mechanisms involved in the generation of a gene with new resistance functions will bring great benefits to future breeding strategies. |
| first_indexed | 2024-03-09T03:29:47Z |
| format | Article |
| id | doaj.art-a2c836c6f71a40579eec6af1aa823cfc |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-09T03:29:47Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-a2c836c6f71a40579eec6af1aa823cfc2023-12-03T14:56:57ZengMDPI AGGenes2073-44252021-01-0112218410.3390/genes12020184The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding StrategiesGiuseppe Andolfo0Nunzio D’Agostino1Luigi Frusciante2Maria Raffaella Ercolano3Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici (NA), ItalyDepartment of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici (NA), ItalyDepartment of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici (NA), ItalyDepartment of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici (NA), ItalyTomato (<i>Solanum lycopersicum</i> L.) is a model system for studying the molecular basis of resistance in plants. The investigation of evolutionary dynamics of tomato resistance (R)-loci provides unique opportunities for identifying factors that promote or constrain genome evolution. Nucleotide-binding domain and leucine-rich repeat (NB-LRR) receptors belong to one of the most plastic and diversified families. The vast amount of genomic data available for Solanaceae and wild tomato relatives provides unprecedented insights into the patterns and mechanisms of evolution of NB-LRR genes. Comparative analysis remarked a reshuffling of R-islands on chromosomes and a high degree of adaptive diversification in key R-loci induced by species-specific pathogen pressure. Unveiling NB-LRR natural variation in tomato and in other Solanaceae species offers the opportunity to effectively exploit genetic diversity in genomic-driven breeding programs with the aim of identifying and introducing new resistances in tomato cultivars. Within this motivating context, we reviewed the repertoire of NB-LRR genes available for tomato improvement with a special focus on signatures of adaptive processes. This issue is still relevant and not thoroughly investigated. We believe that the discovery of mechanisms involved in the generation of a gene with new resistance functions will bring great benefits to future breeding strategies.https://www.mdpi.com/2073-4425/12/2/184R-genesgene clustersNLR genesevolutionary dynamicsgenomic-driven breeding |
| spellingShingle | Giuseppe Andolfo Nunzio D’Agostino Luigi Frusciante Maria Raffaella Ercolano The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies Genes R-genes gene clusters NLR genes evolutionary dynamics genomic-driven breeding |
| title | The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies |
| title_full | The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies |
| title_fullStr | The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies |
| title_full_unstemmed | The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies |
| title_short | The Tomato Interspecific NB-LRR Gene Arsenal and Its Impact on Breeding Strategies |
| title_sort | tomato interspecific nb lrr gene arsenal and its impact on breeding strategies |
| topic | R-genes gene clusters NLR genes evolutionary dynamics genomic-driven breeding |
| url | https://www.mdpi.com/2073-4425/12/2/184 |
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