Methodological Issues in Assessing the Impact of Prenatal Drug Exposure

Prenatal drug exposure is a common public health concern that can result in perinatal complications, birth defects, and developmental disorders. The growing literature regarding the effects of prenatal exposure to specific drugs such as tobacco, alcohol, cocaine, and heroin is often conflicting and...

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Main Author: Carolien Konijnenberg
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Substance Abuse: Research and Treatment
Online Access:https://doi.org/10.4137/SART.S23544
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author Carolien Konijnenberg
author_facet Carolien Konijnenberg
author_sort Carolien Konijnenberg
collection DOAJ
description Prenatal drug exposure is a common public health concern that can result in perinatal complications, birth defects, and developmental disorders. The growing literature regarding the effects of prenatal exposure to specific drugs such as tobacco, alcohol, cocaine, and heroin is often conflicting and constantly changing. This review discusses several reasons why the effects of prenatal drug exposure are so difficult to determine, including variations in dose, timing, duration of exposure, polydrug use, unreliable measures of drug exposure, latent or “sleeper” effects, genetic factors, and socioenvironmental influences. In addition to providing research guidelines, this review also aims to help clinicians and policy makers to identify the strengths and weaknesses in studies investigating the effects of prenatal drug exposure. This knowledge may be used to make better informed decisions regarding the appropriate treatment for pregnant, drug-dependent women and their children.
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spelling doaj.art-a2ccd1a912444713ae83a1b01fb367482022-12-21T19:40:10ZengSAGE PublishingSubstance Abuse: Research and Treatment1178-22182015-01-019s210.4137/SART.S23544Methodological Issues in Assessing the Impact of Prenatal Drug ExposureCarolien Konijnenberg0Department of Psychology, University of Oslo, Oslo, Norway.Prenatal drug exposure is a common public health concern that can result in perinatal complications, birth defects, and developmental disorders. The growing literature regarding the effects of prenatal exposure to specific drugs such as tobacco, alcohol, cocaine, and heroin is often conflicting and constantly changing. This review discusses several reasons why the effects of prenatal drug exposure are so difficult to determine, including variations in dose, timing, duration of exposure, polydrug use, unreliable measures of drug exposure, latent or “sleeper” effects, genetic factors, and socioenvironmental influences. In addition to providing research guidelines, this review also aims to help clinicians and policy makers to identify the strengths and weaknesses in studies investigating the effects of prenatal drug exposure. This knowledge may be used to make better informed decisions regarding the appropriate treatment for pregnant, drug-dependent women and their children.https://doi.org/10.4137/SART.S23544
spellingShingle Carolien Konijnenberg
Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
Substance Abuse: Research and Treatment
title Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
title_full Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
title_fullStr Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
title_full_unstemmed Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
title_short Methodological Issues in Assessing the Impact of Prenatal Drug Exposure
title_sort methodological issues in assessing the impact of prenatal drug exposure
url https://doi.org/10.4137/SART.S23544
work_keys_str_mv AT carolienkonijnenberg methodologicalissuesinassessingtheimpactofprenataldrugexposure