Application of Polyurethane in Drug Delivery System
The feld of drug delivery is a very hot research area as it afects the life of millions of patients every year. Although pharmaceutical agents can be adminisrated in diferent ways, the efectiveness of certain drug delivery sysem (DDS) is directly related to the method of their adminisration. Polyure...
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| Format: | Article |
| Language: | fas |
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Iran Polymer & Petrochemical Institute
2022-02-01
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| Series: | Baspārish |
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| Online Access: | http://basparesh.ippi.ac.ir/article_1798_82194d1f71b57d77f2d8a06b80891848.pdf |
| _version_ | 1811280310154821632 |
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| author | Soheila Ghasemi Milad Ghezelsofloo |
| author_facet | Soheila Ghasemi Milad Ghezelsofloo |
| author_sort | Soheila Ghasemi |
| collection | DOAJ |
| description | The feld of drug delivery is a very hot research area as it afects the life of millions of patients every year. Although pharmaceutical agents can be adminisrated in diferent ways, the efectiveness of certain drug delivery sysem (DDS) is directly related to the method of their adminisration. Polyurethanes are one of the mos important classes of polymers, that play an essential role in the development of many diferent biomedical devices due to their exceptional compatibility, mechanical properties and fexibility. Polyurethanes are formed by the reaction reviewed of isocyanates and diols to produce urethane-bonded polymers (-NH-COO-) in their main chain, which is similar to the peptide bonds in the sructure of proteins. Because of this similarity, they have also been used as part of the human body, such as dialysis membranes, intra-aortic balloons, heart valves, temporary scafolds and breas implants. There are many types of polyurethane sructural blocks available that allow the chemical and physical properties of polyurethane to be tailored to their intended applications, especially in the medical and pharmaceutical felds. In this paper, the synthesis and properties of polyurethane, sructure, thermal sability, hardness, solvent resisance, drug delivery, mechanical properties as well as biodegradability and biocompatibility with special emphasis on the application of the polymer in controlled release of drugs and delivery to the target tissue were. |
| first_indexed | 2024-04-13T01:12:24Z |
| format | Article |
| id | doaj.art-a2cd3f26cb2c40a296c8e978784f62d6 |
| institution | Directory Open Access Journal |
| issn | 2252-0449 2538-5445 |
| language | fas |
| last_indexed | 2024-04-13T01:12:24Z |
| publishDate | 2022-02-01 |
| publisher | Iran Polymer & Petrochemical Institute |
| record_format | Article |
| series | Baspārish |
| spelling | doaj.art-a2cd3f26cb2c40a296c8e978784f62d62022-12-22T03:09:07ZfasIran Polymer & Petrochemical InstituteBaspārish2252-04492538-54452022-02-01114313810.22063/basparesh.2021.2842.15421798Application of Polyurethane in Drug Delivery SystemSoheila Ghasemi0Milad Ghezelsofloo1Faculty of Shiraz UniversityStudent, Department of Chemistry, College of Science, Shiraz University, Shiraz, IranThe feld of drug delivery is a very hot research area as it afects the life of millions of patients every year. Although pharmaceutical agents can be adminisrated in diferent ways, the efectiveness of certain drug delivery sysem (DDS) is directly related to the method of their adminisration. Polyurethanes are one of the mos important classes of polymers, that play an essential role in the development of many diferent biomedical devices due to their exceptional compatibility, mechanical properties and fexibility. Polyurethanes are formed by the reaction reviewed of isocyanates and diols to produce urethane-bonded polymers (-NH-COO-) in their main chain, which is similar to the peptide bonds in the sructure of proteins. Because of this similarity, they have also been used as part of the human body, such as dialysis membranes, intra-aortic balloons, heart valves, temporary scafolds and breas implants. There are many types of polyurethane sructural blocks available that allow the chemical and physical properties of polyurethane to be tailored to their intended applications, especially in the medical and pharmaceutical felds. In this paper, the synthesis and properties of polyurethane, sructure, thermal sability, hardness, solvent resisance, drug delivery, mechanical properties as well as biodegradability and biocompatibility with special emphasis on the application of the polymer in controlled release of drugs and delivery to the target tissue were.http://basparesh.ippi.ac.ir/article_1798_82194d1f71b57d77f2d8a06b80891848.pdfpolyurethanebiocompatibilitybiodegradabilitydrug deliveryintelligent delivery system |
| spellingShingle | Soheila Ghasemi Milad Ghezelsofloo Application of Polyurethane in Drug Delivery System Baspārish polyurethane biocompatibility biodegradability drug delivery intelligent delivery system |
| title | Application of Polyurethane in Drug Delivery System |
| title_full | Application of Polyurethane in Drug Delivery System |
| title_fullStr | Application of Polyurethane in Drug Delivery System |
| title_full_unstemmed | Application of Polyurethane in Drug Delivery System |
| title_short | Application of Polyurethane in Drug Delivery System |
| title_sort | application of polyurethane in drug delivery system |
| topic | polyurethane biocompatibility biodegradability drug delivery intelligent delivery system |
| url | http://basparesh.ippi.ac.ir/article_1798_82194d1f71b57d77f2d8a06b80891848.pdf |
| work_keys_str_mv | AT soheilaghasemi applicationofpolyurethaneindrugdeliverysystem AT miladghezelsofloo applicationofpolyurethaneindrugdeliverysystem |