Intratumoral heterogeneity, treatment response, and survival outcome of ER‐positive HER2‐positive breast cancer

Intratumoral heterogeneity, treatment response, and survival outcome of ER‐positive HER2‐positive breast cancer

Abstract Background ER+HER2+ breast cancer requires most types of systemic therapies perioperatively. However, treatment resistance is often experienced. The current study investigated the predictive and prognostic value of intratumoral heterogeneity and conventional clinicopathological factors in p...

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Bibliographic Details
Main Authors: Natsuki Teruya, Hiroaki Inoue, Rie Horii, Futoshi Akiyama, Takayuki Ueno, Shinji Ohno, Shunji Takahashi
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Cancer Medicine
Subjects:
ER+HER2+ breast cancer
heterogeneity
Ki67
pCR
prognosis
treatment response
Online Access:https://doi.org/10.1002/cam4.5788

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