Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity

Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity

Antje Bruckbauer,1 Michael B Zemel1,21NuSirt Sciences Inc, 2Department of Nutrition, University of Tennessee, Knoxville, TN, USABackground: The purpose of this study was to determine whether a mixture of the polyphenol, resveratrol, and the leucine metabolite, hydroxymethylbutyrate (HMB), acts syner...

Full description

Bibliographic Details
Main Authors:	Bruckbauer A, Zemel MB
Format:	Article
Language:	English
Published:	Dove Medical Press 2013-02-01
Series:	Diabetes, Metabolic Syndrome and Obesity
Online Access:	http://www.dovepress.com/synergistic-effects-of-metformin-resveratrol-and-hydroxymethylbutyrate-a12205

Similar Items

Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice
by: Bruckbauer Antje, et al.
Published: (2012-08-01)

Effects of a leucine and pyridoxine-containing nutraceutical on body weight and composition in obese subjects
by: Zemel MB, et al.
Published: (2013-08-01)

Interaction between leucine and phosphodiesterase 5 inhibition in modulating insulin sensitivity and lipid metabolism
by: Fu L, et al.
Published: (2015-05-01)

Resveratrol, Rapamycin and Metformin as Modulators of Antiviral Pathways
by: Francesca Benedetti, et al.
Published: (2020-12-01)

Metformin Might Inhibit Virus through Increasing Insulin Sensitivity
by: Yong Chen, et al.
Published: (2018-01-01)

Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT.
by: Kahn, SE, et al.
Published: (2011)

Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory markers.
by: Shaymaa A Abdulmalek, et al.
Published: (2019-01-01)

Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study
by: Selenay Furat Rencber, et al.
Published: (2018-06-01)

Synergistic Effects of Resveratrol and Pyrimethanil against Botrytis cinerea on Grape
by: Dandan Xu, et al.
Published: (2018-06-01)

Resveratrol reduces liver endoplasmic reticulum stress and improves insulin sensitivity in vivo and in vitro
by: Zhao H, et al.
Published: (2019-05-01)

Data on biochemical indexes of HFD-fed mice treatment with metformin or resveratrol
by: Wenjun Zhao, et al.
Published: (2016-09-01)

Highly active selenium nanotherapeutics combined with metformin to achieve synergistic sensitizing effect on NK cells for osteosarcoma therapy
by: Du Yanxin, et al.
Published: (2022-06-01)

Evaluating synergistic effects of metformin and simvastatin on ovarian cancer cells.
by: Sara Mikhael, et al.
Published: (2024-01-01)

Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis
by: Xiangyun Zhu, et al.
Published: (2017-09-01)

Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, Microcebus murinus.
by: Julia Marchal, et al.
Published: (2012-01-01)

Therapeutic effect of metformin on patients with polycystic ovary syndrome with normal insulin sensitivity: A retrospective study
by: Wan-Wan Liu, et al.
Published: (2019-01-01)

Elastic-band resistance exercise or vibration treatment in combination with hydroxymethylbutyrate (HMB) supplement for management of sarcopenia in older people: a study protocol for a single-blinded randomised controlled trial in Hong Kong
by: Simon Kwoon-Ho Chow, et al.
Published: (2020-06-01)

Synergistic Beneficial Effects of Resveratrol and Diet on High-Fat Diet-Induced Obesity
by: Osama Abo Alrob, et al.
Published: (2022-09-01)

Are the beneficial cardiovascular effects of simvastatin and metformin also associated with a hormone-dependent mechanism improving insulin sensitivity?
by: C. Bulcão, et al.
Published: (2007-02-01)

Are the beneficial cardiovascular effects of simvastatin and metformin also associated with a hormone-dependent mechanism improving insulin sensitivity?
by: C. Bulcão, et al.

Effects of metformin on insulin resistance after injury in the rat.
by: Frayn, K
Published: (1976)

Protective effects of metformin on neointima formation in insulin resistance
Published: (2013-06-01)

The Synergistic Effects of Resveratrol combined with Resistant Training on Exercise Performance and Physiological Adaption
by: Nai-Wen Kan, et al.
Published: (2018-09-01)

Synergistic anti-tumor effects of liraglutide with metformin on pancreatic cancer cells.
by: Ran Lu, et al.
Published: (2018-01-01)

Tauroursodeoxycholic acid functions as a critical effector mediating insulin sensitization of metformin in obese mice
by: Ya Zhang, et al.
Published: (2022-11-01)

Metformin and Canagliflozin Are Equally Renoprotective in Diabetic Kidney Disease but Have No Synergistic Effect
by: Raphaëlle Corremans, et al.
Published: (2023-05-01)

Are There Differences in Gut Microbiome in Patients with Type 2 Diabetes Treated by Metformin or Metformin and Insulin?
by: Dzięgielewska-Gęsiak S, et al.
Published: (2022-11-01)

Could Metformin and Resveratrol Support Glioblastoma Treatment? A Mechanistic View at the Cellular Level
by: Raghad Sabaawi Ibrahim, et al.
Published: (2023-06-01)

Effect of Metformin on Parameters of Insulin Resistance in Patients with Primary Hypothyroidism
by: Tamara Vatseba
Published: (2017-03-01)

The effect of Metformin on fibrocystic breast disease in women with insulin resistance
by: E. V. Musina, et al.
Published: (2018-10-01)

Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications
by: Liu Y, et al.
Published: (2020-09-01)

Curcumin- and resveratrol-co-loaded nanoparticles in synergistic treatment of hepatocellular carcinoma
by: Yongshun Zheng, et al.
Published: (2022-07-01)

The Synergistic Glucose-lowering Effects of Metformin and Bavachinin on Type II Diabetic Rats
by: Sara Khosraviani, et al.
Published: (2023-05-01)

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks
by: Vincenzo Sorrenti, et al.
Published: (2022-07-01)

Insulin resistance accelerated the clearance of resveratrol: A note of caution
by: Zhixia Qiu, et al.
Published: (2019-07-01)

LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol.
by: Mark K Nøhr, et al.
Published: (2016-01-01)

The effects of metformin on hyperandrogenism and menstrual functions in insulin resistant adolescents with PCOS
by: Recai Pabuçcu, et al.
Published: (2022-05-01)

Effects Of Metformin In Insulin – Treated Type 2 Diabetes Mellitus Patients
by: Nakhjavani M, et al.
Published: (2005-06-01)

Synergistic association of resveratrol and histone deacetylase inhibitors as treatment in amyotrophic lateral sclerosis
by: Edoardo Parrella, et al.
Published: (2022-10-01)

A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy
by: Qicai Xiao, et al.
Published: (2019-01-01)