Genotypic and phenotypic comparison of drug resistance profiles of clinical multidrug-resistant Mycobacterium tuberculosis isolates using whole genome sequencing in Latvia

Genotypic and phenotypic comparison of drug resistance profiles of clinical multidrug-resistant Mycobacterium tuberculosis isolates using whole genome sequencing in Latvia

Abstract Background Multidrug-resistant tuberculosis (MDR–TB) remains a major public health problem in many high tuberculosis (TB) burden countries. Phenotypic drug susceptibility testing (DST) take several weeks or months to result, but line probe assays and Xpert/Rif Ultra assay detect a limited n...

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Bibliographic Details
Main Authors: Anda Vīksna, Darja Sadovska, Iveta Berge, Ineta Bogdanova, Annija Vaivode, Lauma Freimane, Inga Norvaiša, Iveta Ozere, Renāte Ranka
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Infectious Diseases
Subjects:
Drug-resistant tuberculosis
Whole genome sequencing
Drug susceptibility testing
Latvia
Online Access:https://doi.org/10.1186/s12879-023-08629-7

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