Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms
A family of N,N-bis(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms was synthesized by the microwave-assisted and catalyst-free Kabachnik–Fields reaction of (aminomethyl)phosphine oxides with paraformaldehyde and diphenylphosphine oxide. The three-component condensati...
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2019-02-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.15.40 |
| _version_ | 1818617532513255424 |
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| author | Erika Bálint Anna Tripolszky László Hegedűs György Keglevich |
| author_facet | Erika Bálint Anna Tripolszky László Hegedűs György Keglevich |
| author_sort | Erika Bálint |
| collection | DOAJ |
| description | A family of N,N-bis(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms was synthesized by the microwave-assisted and catalyst-free Kabachnik–Fields reaction of (aminomethyl)phosphine oxides with paraformaldehyde and diphenylphosphine oxide. The three-component condensation of N,N-bis(phosphinoylmethyl)amine, paraformaldehyde and a secondary phosphine oxide affording N,N,N-tris(phosphinoylmethyl)amine derivatives was also elaborated. This method is a novel approach for the synthesis of the target products. |
| first_indexed | 2024-12-16T17:07:12Z |
| format | Article |
| id | doaj.art-a2d722f904c645399bd39176d0c23de3 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-16T17:07:12Z |
| publishDate | 2019-02-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-a2d722f904c645399bd39176d0c23de32022-12-21T22:23:32ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972019-02-0115146947310.3762/bjoc.15.401860-5397-15-40Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atomsErika Bálint0Anna Tripolszky1László Hegedűs2György Keglevich3Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, HungaryDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, HungaryDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, HungaryDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, HungaryA family of N,N-bis(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms was synthesized by the microwave-assisted and catalyst-free Kabachnik–Fields reaction of (aminomethyl)phosphine oxides with paraformaldehyde and diphenylphosphine oxide. The three-component condensation of N,N-bis(phosphinoylmethyl)amine, paraformaldehyde and a secondary phosphine oxide affording N,N,N-tris(phosphinoylmethyl)amine derivatives was also elaborated. This method is a novel approach for the synthesis of the target products.https://doi.org/10.3762/bjoc.15.40(aminomethyl)phosphine oxidesKabachnik–Fields reactionligandmicrowaveN,N-bis(phosphinoylmethyl)aminesN,N,N-tris(phosphinoylmethyl)amines |
| spellingShingle | Erika Bálint Anna Tripolszky László Hegedűs György Keglevich Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms Beilstein Journal of Organic Chemistry (aminomethyl)phosphine oxides Kabachnik–Fields reaction ligand microwave N,N-bis(phosphinoylmethyl)amines N,N,N-tris(phosphinoylmethyl)amines |
| title | Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms |
| title_full | Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms |
| title_fullStr | Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms |
| title_full_unstemmed | Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms |
| title_short | Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms |
| title_sort | microwave assisted synthesis of n n bis phosphinoylmethyl amines and n n n tris phosphinoylmethyl amines bearing different substituents on the phosphorus atoms |
| topic | (aminomethyl)phosphine oxides Kabachnik–Fields reaction ligand microwave N,N-bis(phosphinoylmethyl)amines N,N,N-tris(phosphinoylmethyl)amines |
| url | https://doi.org/10.3762/bjoc.15.40 |
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