Anticancer of genus Syzygium: a systematic review
Aim: One in eight fatalities globally are considered cancer-related. The need for cancer therapy is growing. Natural products continue to play a role in drug development, as up to 50% of authorized drugs in the last 30 years have been isolated from natural sources. Methods: Anticancer, antioxidant,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2023-04-01
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| Series: | Exploration of Targeted Anti-tumor Therapy |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/Journals/etat/Article/1002134 |
| _version_ | 1827954121833971712 |
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| author | Mahmoud Dogara Abdulrahman Harmand A. Hama |
| author_facet | Mahmoud Dogara Abdulrahman Harmand A. Hama |
| author_sort | Mahmoud Dogara Abdulrahman |
| collection | DOAJ |
| description | Aim: One in eight fatalities globally are considered cancer-related. The need for cancer therapy is growing. Natural products continue to play a role in drug development, as up to 50% of authorized drugs in the last 30 years have been isolated from natural sources.
Methods: Anticancer, antioxidant, antibacterial, antifungal, antiviral, analgesic, anti-inflammatory, and other actions have all been reported in research papers using plants from the Syzygium genus in the treatment and prevention of disease.
Results: Results from the anticancer test showed that the genus, especially Syzygium aqueum, Syzygium samarangense, and Syzygium cumini had significant promise as an anticancer agent in vitro against several cancer cell lines. Numerous factors, including phytochemical composition, increased apoptotic activity, decreased cell proliferation, stopped angiogenesis, and reduced inflammation.
Conclusions: These results, despite preliminary, show promise for further purification and investigation of bioactive compounds and extracts within the genus Syzygium for their anticancer properties. |
| first_indexed | 2024-04-09T14:24:07Z |
| format | Article |
| id | doaj.art-a2d9fd6d9ed048cf9369a4ba7d9d4e26 |
| institution | Directory Open Access Journal |
| issn | 2692-3114 |
| language | English |
| last_indexed | 2024-04-09T14:24:07Z |
| publishDate | 2023-04-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Targeted Anti-tumor Therapy |
| spelling | doaj.art-a2d9fd6d9ed048cf9369a4ba7d9d4e262023-05-04T09:40:32ZengOpen Exploration Publishing Inc.Exploration of Targeted Anti-tumor Therapy2692-31142023-04-014227329310.37349/etat.2023.00134Anticancer of genus Syzygium: a systematic reviewMahmoud Dogara Abdulrahman0https://orcid.org/0000-0003-0944-7282Harmand A. Hama1https://orcid.org/0000-0003-1307-4271Biology Education Department, Faculty of Education, Tishk International University, Kurdistan Region, Erbil 44001, IraqBiology Education Department, Faculty of Education, Tishk International University, Kurdistan Region, Erbil 44001, IraqAim: One in eight fatalities globally are considered cancer-related. The need for cancer therapy is growing. Natural products continue to play a role in drug development, as up to 50% of authorized drugs in the last 30 years have been isolated from natural sources. Methods: Anticancer, antioxidant, antibacterial, antifungal, antiviral, analgesic, anti-inflammatory, and other actions have all been reported in research papers using plants from the Syzygium genus in the treatment and prevention of disease. Results: Results from the anticancer test showed that the genus, especially Syzygium aqueum, Syzygium samarangense, and Syzygium cumini had significant promise as an anticancer agent in vitro against several cancer cell lines. Numerous factors, including phytochemical composition, increased apoptotic activity, decreased cell proliferation, stopped angiogenesis, and reduced inflammation. Conclusions: These results, despite preliminary, show promise for further purification and investigation of bioactive compounds and extracts within the genus Syzygium for their anticancer properties. https://www.explorationpub.com/Journals/etat/Article/1002134anticanceractivitycancerplants |
| spellingShingle | Mahmoud Dogara Abdulrahman Harmand A. Hama Anticancer of genus Syzygium: a systematic review Exploration of Targeted Anti-tumor Therapy anticancer activity cancer plants |
| title | Anticancer of genus Syzygium: a systematic review |
| title_full | Anticancer of genus Syzygium: a systematic review |
| title_fullStr | Anticancer of genus Syzygium: a systematic review |
| title_full_unstemmed | Anticancer of genus Syzygium: a systematic review |
| title_short | Anticancer of genus Syzygium: a systematic review |
| title_sort | anticancer of genus syzygium a systematic review |
| topic | anticancer activity cancer plants |
| url | https://www.explorationpub.com/Journals/etat/Article/1002134 |
| work_keys_str_mv | AT mahmouddogaraabdulrahman anticancerofgenussyzygiumasystematicreview AT harmandahama anticancerofgenussyzygiumasystematicreview |