Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.

Bibliographic Details
Main Authors: Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter, Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe, Marc Erhardt
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15738-3

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