Acetaminophen Attenuates Obesity-Related Renal Injury Through ER-Mediated Stress Mechanisms

Acetaminophen Attenuates Obesity-Related Renal Injury Through ER-Mediated Stress Mechanisms

Background/Aims: Obesity is an independent risk factor for the development of kidney disease. The purpose of this study was to determine how obesity may contribute to renal damage and whether acetaminophen ingestion can diminish obesity-associated renal cell injury in the obese Zucker rat model. Met...

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Bibliographic Details
Main Authors: Cuifen Wang, Miaozong Wu, Ravikumar Arvapalli, Xiaoniu Dai, Muhammad Mahmood, Henry Driscoll, Kevin M. Rice, Eric Blough
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Apoptosis
Endoplasmic reticulum stress
Lipotoxicity
Obesity
Acetaminophen
Kidney
Online Access:http://www.karger.com/Article/FullText/358683

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